Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 10/20 | 0.67 |
| ▸ | MMP13 | P45452 | 2/20 | 0.59 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | SCD | O00767 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | PRKCG | P05129 | 1/20 | 0.41 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | PRKX | P51817 | 1/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.41 |
| ▸ | PRKG2 | Q13237 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5957599 | 0.99 | TRPA1 (0.66) | TRPA1MMP13EGLN1ALDH1A1BRD4 | |
| Hydrochloric Acid SCHEMBL5957820 | 0.99 | TRPA1 (0.66) | TRPA1MMP13EGLN1ALDH1A1BRD4 | |
| SCHEMBL5957700 | 0.94 | MMP13 (0.66) | TRPA1MMP13 | |
| SCHEMBL5957426 | 0.89 | TRPA1 (0.67) | TRPA1MMP13ALDH1A1LMNAMAP4K4 | |
| SCHEMBL5957667 | 0.88 | TRPA1 (0.67) | TRPA1MMP13ALDH1A1MAPK1 | |
| SCHEMBL5957566 | 0.86 | MMP13 (0.57) | TRPA1MMP13ALDH1A1 | |
| SCHEMBL7106604 | 0.84 | MMP13 (0.60) | TRPA1MMP13MAPK1GSK3B | |
| SCHEMBL5957475 | 0.82 | MMP13 (0.88) | TRPA1MMP13ALDH1A1LMNAGSK3B | |
| Hydrochloric Acid SCHEMBL5957471 | 0.81 | MMP13 (0.86) | TRPA1MMP13ALDH1A1LMNAGSK3B | |
| SCHEMBL5957784 | 0.80 | TRPA1 (1.00) | TRPA1ALDH1A1BRD4SCDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060040957-A1 | BICYCLIC PYRIMIDINE MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY | 2006-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060040957-A1 | BICYCLIC PYRIMIDINE MATRIX METALLOPROTEINASE INHIBITORS | MMP13, MMP25, MMP15 | TRPA1 3405/4885MMP13 1/4885EGLN1 783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.