SCHEMBL5960883

SCHEMBL5960883

Oc1cccc(Br)c1-c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP4 P15090 1/20 0.46
GUSB P08236 1/20 0.45
CRHBP P24387 1/20 0.45
CRHR2 Q13324 1/20 0.45
ALDH1A1 P00352 4/20 0.44
BACE1 P56817 3/20 0.44
HPGD P15428 2/20 0.44
HSD17B10 Q99714 2/20 0.44
BCL2L1 Q07817 2/20 0.44
MAPK1 P28482 2/20 0.44
HDAC4 P56524 1/20 0.42
HDAC2 Q92769 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
CYP3A4 P08684 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
HSD17B1 P14061 1/20 0.40
CYP2B6 P20813 1/20 0.40
CYP2C19 P33261 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28156836 0.84 ALDH1A1 (0.41) FABP4GUSBALDH1A1BACE1HPGD
SCHEMBL8158458 0.84 ALDH1A1 (0.54) FABP4GUSBCRHBPCRHR2ALDH1A1
SCHEMBL8973903 0.83 ALDH1A1 (0.55) FABP4CRHBPCRHR2ALDH1A1MAPK1
SCHEMBL355552 0.83 ALDH1A1 (0.55) ALDH1A1BACE1HPGDHSD17B10BCL2L1
SCHEMBL8157958 0.82 CRHBP (0.45) FABP4CRHBPCRHR2ALDH1A1BACE1
SCHEMBL25893532 0.79 ALOX5 (0.44) GUSBALDH1A1CYP3A4CYP1A2CYP2D6
SCHEMBL8158462 0.79 ALDH1A1 (0.59) CRHBPCRHR2ALDH1A1BACE1HPGD
SCHEMBL15714371 0.78 ALDH1A1 (0.55) FABP4CRHBPCRHR2ALDH1A1HSD17B10
SCHEMBL3979829 0.77 CA2 (0.47) GUSBALDH1A1BACE1HPGDHSD17B10
SCHEMBL8726752 0.76 ALDH1A1 (0.61) ALDH1A1BACE1HPGDHSD17B10BCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112268899-A Method for rapidly identifying fritillaria medicinal materials 成都中医药大学 2021-01-26 CN claimed
US-6458993-B1 AROMATIC CYANATE ESTER COMPOUNDS HAVING AT LEAST TWO RINGS LINKED BY AN UNSATURATED GROUP CONTAINING MEMBER CAN BE EMPLOYED IN ADHESIVES, COMPOSITES, LAMINATES AND MOLDINGS VANTICO INC. 2002-10-01 US claimed
US-20020055648-A1 Cyanate esters having flame resistant properties JPMORGAN CHASE BANK, N.A. 2002-05-09 US claimed
CN-112268899-A Method for rapidly identifying fritillaria medicinal materials 成都中医药大学 2021-01-26 CN disclosed
CN-106719641-B Protaetia brevitarsis attractant and preparation method thereof 河北省农林科学院植物保护研究所 2019-10-22 CN disclosed
CN-108117541-A Preparation and mechanism research of high-efficiency phosphorescent pure organic long-afterglow material 南京工业大学 2018-06-05 CN disclosed
CN-108024563-A Improve the increased biomembrane composite inhibiting of weight in domestic animal 艾索生物医药公司 2018-05-11 CN disclosed
CN-106719641-A Protaetia brevitarsis attractant and preparation method thereof 河北省农林科学院植物保护研究所 2017-05-31 CN disclosed
WO-2016175533-A2 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME 덕산네오룩스 주식회사 2016-11-03 WO disclosed
WO-2016175533-A2 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME 덕산네오룩스 주식회사 2016-11-03 WO disclosed
CN-103492954-A Toner, and full-color image forming method and full-color image forming apparatus using the toner RICOH CO LTD 2014-01-01 CN disclosed
EP-0953634-A1 COMPOSITION FOR TREATING POROUS ARTICLE, TREATMENT METHOD, AND USE THEREOF SHOWA DENKO KABUSHIKI KAISHA (JP) 1999-11-03 EP disclosed
EP-0914080-A1 AGENT AND PROCESS FOR DYEING AND TINTING KERATINOUS FIBRES Henkel Kommanditgesellschaft auf Aktien (DE) 1999-05-12 EP disclosed
WO-1999020230-A2 HAIR MASCARA HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1999-04-29 WO disclosed
EP-0910332-A2 DYES Hans Schwarzkopf GmbH & Co. KG (DE) 1999-04-28 EP disclosed
WO-1998001105-A2 DYES HANS SCHWARZKOPF GMBH & CO. KG (DE) 1998-01-15 WO disclosed
WO-1997042932-A1 AGENT AND PROCESS FOR DYEING AND TINTING KERATINOUS FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1997-11-20 WO disclosed
EP-0532176-B1 Laser-sensitive electrophotographic lithograph printing plate material OJI PAPER CO (JP) 1995-05-17 EP disclosed
US-5362590-A Substrates with light sensitive photoconductor layers with cyanine dyes and antioxidants OJI PAPER CO., LTD. (JP) 1994-11-08 US disclosed
EP-0532176-A1 Laser-sensitive electrophotographic lithograph printing plate material NEW OJI PAPER CO., LTD. (JP) 1993-03-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020055648-A1 Cyanate esters having flame resistant properties PCCA, FABP4, MCCC2 FABP4 2/4885GUSB 3596/4885CRHBP 3521/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.