Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 4/20 | 0.37 |
| ▸ | GSK3A | P49840 | 2/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | GHSR | Q92847 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5963658 | 0.86 | AKR1B1 (0.40) | PDE7BGSK3BPDE7AAKR1B1 | |
| SCHEMBL5963932 | 0.86 | KMT2A (0.40) | PDE7BPDE7A | |
| SCHEMBL5963591 | 0.85 | SLC6A4 (0.43) | PDE7BPDE7ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5963352 | 0.84 | SMN1; SMN2 (0.47) | TP53PDE7ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5963733 | 0.84 | PDE7A (0.41) | PDE7BPDE7ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5963779 | 0.82 | PGR (0.43) | PDE7BPGRTP53GSK3BGSK3A | |
| SCHEMBL5963585 | 0.81 | POLB (0.42) | PDE7BADORA2AAKR1B1 | |
| SCHEMBL5963968 | 0.80 | PDE7B (0.38) | PDE7BGSK3BGSK3APDE7ASLC6A4 | |
| SCHEMBL5964489 | 0.79 | FPR2 (0.40) | PDE7BAKR1B1 | |
| SCHEMBL5963527 | 0.79 | ALDH1A1 (0.42) | PDE7BSLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7125840-B2 | Substituted dipeptides as growth hormone secretagogues | ELI LILLY AND COMPANY (US) | 2006-10-24 | — | — | US | disclosed |
| US-20040058971-A1 | Substituted dipeptides as growth hormone secretagogues | ELI LILLY AND COMPANY | 2004-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058971-A1 | Substituted dipeptides as growth hormone secretagogues | GHSR, GHRHR, SSTR4 | PDE7B 1268/4885PGR 813/4885TP53 3810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.