Water

Water

SCHEMBL596607

B=O.O.[MgH2]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1289401 0.89
Water SCHEMBL10948343 0.80
Water SCHEMBL20137417 0.80
Water SCHEMBL3621433 0.80
Water SCHEMBL28489794 0.80
SCHEMBL297988 0.78
Water SCHEMBL27683481 0.73
Water SCHEMBL700314 0.73
SCHEMBL23391294 0.67
Phosphine SCHEMBL7096319 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107848893-B COG dielectric composition for use with nickel electrodes 费罗公司 2021-12-31 CN disclosed
EP-3892600-A1 COG DIELECTRIC COMPOSITION FOR USE WTH NICKEL ELECTRODES Ferro Corporation (US) 2021-10-13 EP disclosed
EP-3268329-A1 COG DIELECTRIC COMPOSITION FOR USE WITH NICKEL ELECTRODES Ferro Corporation (US) 2018-01-17 EP disclosed
US-9852848-B2 COG dielectric composition for use with nickel electrodes FERRO CORPORATION (US) 2017-12-26 US disclosed
US-20170200557-A1 COG Dielectric Composition For Use With Nickel Electrodes CREDIT SUISSE AG, CAYMAN ISLANDS BRANCH, AS ADMINISTRATIVE AGENT 2017-07-13 US disclosed
US-9704650-B2 COG dielectric composition for use with nickel electrodes FERRO CORPORATION (US) 2017-07-11 US disclosed
US-20160240313-A1 COG Dielectric Composition For Use With Nickel Electrodes CREDIT SUISSE AG, CAYMAN ISLANDS BRANCH, AS ADMINISTRATIVE AGENT 2016-08-18 US disclosed
CN-101484560-B Refrigerator oil, compressor oil composition, hydraulic working oil composition, metal working oil composition, heat treatment oil composition, lubricating oil composition for machine tool, and lubricating oil composition NIPPON OIL CORP 2013-03-27 CN disclosed
US-8114801-B2 COG dieletric composition for use with nickel electrodes FERRO CORPORATION (US) 2012-02-14 US disclosed
US-20110090619-A1 COG Dieletric Composition For Use With Nickel Electrodes FERRO CORPORATION (US) 2011-04-21 US disclosed
US-7858548-B2 COG dielectric composition for use with nickel electrodes FERRO CORPORATION (US) 2010-12-28 US disclosed
CN-101090960-B Lubricating base oil, lubricating oil composition for internal combustion engine, and lubricating oil composition for drive transmission device NIPPON OIL CORP 2010-10-27 CN disclosed
CN-101484560-A Refrigerator oil, compressor oil composition, hydraulic working oil composition, metal working oil composition, heat treatment oil composition, lubricating oil composition for machine tool, and lubricating oil composition NIPPON OIL CORP (JP) 2009-07-15 CN disclosed
CN-101454431-A Lubricating oil base oil, preparation method thereof and lubricating oil composition NIPPON OIL CORP (JP) 2009-06-10 CN disclosed
CN-101379171-A Lubricant base oil, lubricating oil composition for internal combustion engine, and lubricating oil composition for transmission device NIPPON OIL CORP (JP) 2009-03-04 CN disclosed
CN-101272991-A COG dielectric composition for use with nickel electrodes FERRO CORP (US) 2008-09-24 CN disclosed
US-20080063881-A1 Cog Dielectric Composition For Use With Nickel Electrodes CREDIT SUISSE AG, CAYMAN ISLANDS BRANCH, AS ADMINISTRATIVE AGENT 2008-03-13 US disclosed
CN-101090960-A Lubricating base oil, lubricating oil composition for internal combustion engine, and lubricating oil composition for drive transmission device NIPPON OIL CORP (JP) 2007-12-19 CN disclosed
WO-2007037973-A1 COG DIELECTRIC COMPOSITION FOR USE WITH NICKEL ELECTRODES FERRO CORPORATION (US) 2007-04-05 WO disclosed
US-4375566-A Process for producing ortho-alkylated phenols from anisoles MITSUI TOATSU CHEMICALS, INC. (JP) 1983-03-01 US disclosed