Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CYTH3 | O43739 | 1/20 | 0.30 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
| ▸ | EPN1 | Q9Y6I3 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26820 | 0.83 | HPGD (0.54) | HPGDHCAR2DAOCYTH3BTK | |
| SCHEMBL42514 | 0.81 | HPGD (0.52) | HPGDDYRK1AHCAR2DAOLMNA | |
| Hydrochloric Acid SCHEMBL27727584 | 0.81 | HPGD (0.52) | HPGDHCAR2DAOCYTH3BTK | |
| SCHEMBL5013388 | 0.81 | HPGD (0.52) | HPGDDYRK1AHCAR2DAOLMNA | |
| SCHEMBL15981916 | 0.81 | HPGD (0.52) | HPGDDYRK1AHCAR2DAOLMNA | |
| SCHEMBL17928435 | 0.78 | HPGD (0.49) | HPGDDYRK1AHCAR2DAOLMNA | |
| SCHEMBL18680106 | 0.77 | HPGD (0.49) | HPGDDYRK1AHCAR2DAOLMNA | |
| SCHEMBL25449 | 0.77 | MAPK1 (0.57) | HPGDDYRK1AHCAR2SMN1; SMN2MEN1 | |
| SCHEMBL6305513 | 0.77 | HPGD (0.49) | HPGDDYRK1AHCAR2DAOLMNA | |
| SCHEMBL14620257 | 0.77 | HPGD (0.49) | HPGDDYRK1AHCAR2DAOALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060128608-A1 | Novel chemical compounds and their use | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2006-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128608-A1 | Novel chemical compounds and their use | PGLS, ABCG2, UGCG | HPGD 252/4885CA1 4456/4885CA2 2364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.