SCHEMBL598129

SCHEMBL598129

Nc1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)C1N

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 4/20 1.00
POLB P06746 1/20 1.00
ADORA1 P30542 2/20 0.82
PI4KA P42356 2/20 0.82
PI4K2B Q8TCG2 2/20 0.82
PI4K2A Q9BTU6 2/20 0.82
PI4KB Q9UBF8 2/20 0.82
DPP4 P27487 1/20 0.82
MEN1 O00255 1/20 0.82
SLC28A1 O00337 1/20 0.82
MAP3K7 O43318 1/20 0.82
SLC28A2 O43868 1/20 0.82
GAPDH P04406 1/20 0.82
MAPK1 P28482 1/20 0.82
ADORA2A P29274 1/20 0.82
ADORA2B P29275 1/20 0.82
STAT6 P42226 1/20 0.82
KMT2A Q03164 1/20 0.82
SMN1; SMN2 Q16637 1/20 0.82
DOT1L Q8TEK3 1/20 0.82

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28669338 1.00 ADORA3 (1.00) ADORA3POLBADORA1PI4KAPI4K2B
SCHEMBL14580082 1.00 ADORA3 (1.00) ADORA3POLBADORA1PI4KAPI4K2B
SCHEMBL29537510 1.00 ADORA3 (1.00) ADORA3POLBADORA1PI4KAPI4K2B
SCHEMBL14565261 1.00 ADORA3 (1.00) ADORA3POLBADORA1PI4KAPI4K2B
SCHEMBL939272 1.00 ADORA3 (1.00) ADORA3POLBADORA1PI4KAPI4K2B
SCHEMBL598131 1.00 ADORA3 (1.00) ADORA3POLBADORA1PI4KAPI4K2B
SCHEMBL598130 1.00 ADORA3 (1.00) ADORA3POLBADORA1PI4KAPI4K2B
SCHEMBL4204378 1.00 ADORA3 (1.00) ADORA3POLBADORA1PI4KAPI4K2B
SCHEMBL7153060 1.00 ADORA3 (1.00) ADORA3POLBADORA1PI4KAPI4K2B
SCHEMBL7153080 1.00 ADORA3 (1.00) ADORA3POLBADORA1PI4KAPI4K2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 373 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250263678-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA REJUVENATION TECHNOLOGIES, INC. (US) 2025-08-21 US claimed
EP-4379052-A2 MRNA PURIFICATION BY TANGENTIAL FLOW FILTRATION Ethris GmbH (DE) 2024-06-05 EP claimed
EP-4306643-A2 PLASMID CONTAINING A SEQUENCE ENCODING AN MRNA WITH A SEGMENTED POLY(A) TAIL ethris GmbH (DE) 2024-01-17 EP claimed
EP-4271389-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA Rejuvenation Technologies Inc. (US) 2023-11-08 EP claimed
WO-2022147039-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA REJUVENATION TECHNOLOGIES INC. (US) 2022-07-07 WO claimed
US-20220002737-A1 ARTIFICIAL NUCLEIC ACID MOLECULES FOR IMPROVED PROTEIN EXPRESSION CUREVAC AG (DE) 2022-01-06 US claimed
EP-1229040-B1 Nucleoside monophosphate derivative, a processor for their production and their use as immunosuppressive drugs HEIDELBERG PHARMA HOLDING GMBH (DE) 2003-09-10 EP claimed
EP-1229040-A2 Nucleoside monophosphate derivative, a processor for their production and their use as immunosuppressive drugs Heidelberg Pharma Holding GmbH (DE) 2002-08-07 EP claimed
US-6025343-A Lipid esters of nucleoside monophosphates and their use as immunosuppressive drugs ROCHE DIAGNOSTICS GMBH (DE) 2000-02-15 US claimed
EP-4746905-A1 RSV VACCINE Astrazeneca AB (SE) 2026-05-27 EP disclosed
WO-2026104647-A1 VACCINE ASTRAZENECA AB (SE) 2026-05-21 WO disclosed
US-20260103746-A1 PROCESS FOR THE PRODUCTION OF CLOSED LINEAR DNA TYRIS THERAPEUTICS S L (ES) 2026-04-16 US disclosed
US-20260085315-A1 POLYNUCLEOTIDE COMPOSITIONS AND METHODS FOR TREATMENT OF CANCER APTAH BIO INC (US) 2026-03-26 US disclosed
US-20260069718-A1 Engineered Guide RNAs and Polynucleotides SHAPE THERAPEUTICS INC (US) 2026-03-12 US disclosed
WO-1991010671-A1 COMPOSITIONS AND METHODS FOR DETECTING AND MODULATING RNA ACTIVITY AND GENE EXPRESSION ISIS PHARMACEUTICALS, INC. (US) 1991-07-25 WO disclosed
US-5015733-A Phosphoramidites and oligonucleotides derived therefrom CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1991-05-14 US disclosed
US-4849513-A Deoxyribonucleoside phosphoramidites in which an aliphatic amino group is attached to the sugar ring and their use for the preparation of oligonucleotides containing aliphatic amino groups CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1989-07-18 US disclosed
EP-0270651-A4 NOVEL DEOXYRIBONUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE FOR THE PREPARATION OF OLIGONUCLEOTIDES. CALIFORNIA INST OF TECHN (US) 1989-03-29 EP disclosed
EP-0270651-A1 NOVEL DEOXYRIBONUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE FOR THE PREPARATION OF OLIGONUCLEOTIDES. CALIFORNIA INST OF TECHN (US) 1988-06-15 EP disclosed
WO-1988000201-A1 NOVEL DEOXYRIBONUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE FOR THE PREPARATION OF OLIGONUCLEOTIDES CALIFORNIA INSTITUTE OF TECHNOLOGY, INC. (US) 1988-01-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260069718-A1 Engineered Guide RNAs and Polynucleotides SNCA, CDA, UPF1 ADORA3 772/4885POLB 178/4885ADORA1 1093/4885
US-20260085315-A1 POLYNUCLEOTIDE COMPOSITIONS AND METHODS FOR TREATMENT OF CANCER RPRD2, RTCB, UPF1 ADORA3 2418/4885POLB 224/4885ADORA1 3915/4885
US-20250263678-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA RNASE1, POLRMT, TERT ADORA3 4335/4885POLB 82/4885ADORA1 4370/4885
US-20220002737-A1 ARTIFICIAL NUCLEIC ACID MOLECULES FOR IMPROVED PROTEIN EXPRESSION CPSF6, CPSF1, RNMT ADORA3 474/4885POLB 464/4885ADORA1 1472/4885
US-20260103746-A1 PROCESS FOR THE PRODUCTION OF CLOSED LINEAR DNA POLM, POLL, POLB ADORA3 2990/4885POLB 3/4885ADORA1 3149/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.