Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.34 |
| ▸ | CTSS | P25774 | 3/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5983441 | 0.78 | NFKB1 (0.36) | ALDH1A1LMNAATMCTSSCTSK | |
| Methane SCHEMBL27537449 | 0.77 | NFKB1 (0.36) | ALDH1A1LMNAATMCTSSCTSK | |
| SCHEMBL5984433 | 0.73 | ALDH1A1 (0.36) | ALDH1A1CACNA1GKDM4EMEN1MAPT | |
| SCHEMBL28459748 | 0.68 | KLK5 (0.36) | ATMCTSSCTSKCTSLCTSB | |
| SCHEMBL8970782 | 0.67 | MEN1 (0.38) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL28461037 | 0.67 | CTSS (0.36) | ATMCTSSCTSKCTSLCTSB | |
| SCHEMBL28443486 | 0.66 | KCNN4 (0.36) | ALDH1A1LMNAMEN1MAPTKMT2A | |
| SCHEMBL5182782 | 0.65 | MEN1 (0.39) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL19746580 | 0.65 | MEN1 (0.42) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL23928823 | 0.65 | NFKB1 (0.37) | ALDH1A1LMNACTSSCTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1667959-A1 | BIPHENYLOXY-ACIDS | Wyeth (US) | 2006-06-14 | — | — | EP | disclosed |
| WO-2005030702-A1 | BIPHENYLOXY-ACIDS | WYETH (US) | 2005-04-07 | — | — | WO | disclosed |