Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | PTPRG | P23470 | 3/20 | 0.40 |
| ▸ | PTPRC | P08575 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 2/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8391826 | 0.82 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2TP53TSHRCASP1 | |
| SCHEMBL1780269 | 0.81 | GAA (0.36) | ALDH1A1SMN1; SMN2TP53TSHRCASP1 | |
| SCHEMBL8726320 | 0.81 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2TP53TSHRCASP1 | |
| SCHEMBL9952673 | 0.78 | TSHR (0.52) | ALDH1A1TP53TSHRPTPRGKDM4E | |
| Hexane SCHEMBL8729907 | 0.77 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2TP53TSHRCASP1 | |
| SCHEMBL1636013 | 0.76 | TAS2R14 (0.40) | ALDH1A1KDM4ENOTUMUSP2HPGD | |
| SCHEMBL27544752 | 0.74 | CSNK2A2 (0.49) | ALDH1A1SMN1; SMN2TP53TSHRCASP1 | |
| SCHEMBL598480 | 0.74 | PTGS2 (0.42) | ALDH1A1SMN1; SMN2TP53TSHRCASP1 | |
| SCHEMBL9709807 | 0.73 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2TP53TSHRCASP1 | |
| SCHEMBL17494887 | 0.73 | HSD17B10 (0.39) | ALDH1A1SMN1; SMN2TSHRPTPRGPTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2296473-B1 | HERBICIDALLY EFFECTIVE 4- (3-ALKYL SULFINYL BENZOYL) PYRAZOLES | BAYER CROPSCIENCE AG (DE) | 2012-07-11 | — | — | EP | disclosed |
| US-8114816-B2 | Herbicidally active 4-(3-alkylsulfinylbenzoyl)pyrazoles | BAYER CROPSCIENCE AG (DE) | 2012-02-14 | — | — | US | disclosed |
| EP-2296473-A2 | HERBICIDALLY EFFECTIVE 4- (3-ALKYL SULFINYL BENZOYL) PYRAZOLES | Bayer CropScience AG (DE) | 2011-03-23 | — | — | EP | disclosed |
| US-20100004129-A1 | HERBICIDALLY ACTIVE 4-(3-ALKYLSULFINYLBENZOYL)PYRAZOLES | BAYER CROPSCIENCE AG (DE) | 2010-01-07 | — | — | US | disclosed |
| WO-2009149806-A2 | HERBICIDALLY EFFECTIVE 4- (3-ALKYL SULFINYL BENZOYL) PYRAZOLES | BAYER CROPSCIENCE AG (DE) | 2009-12-17 | — | — | WO | disclosed |
| EP-2127521-A1 | 4-(3-Alkylsulfinylbenzoyl)pyrazoles as herbicides | Bayer CropScience Aktiengesellschaft (DE) | 2009-12-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100004129-A1 | HERBICIDALLY ACTIVE 4-(3-ALKYLSULFINYLBENZOYL)PYRAZOLES | CYP4X1, PRDX4, CBR3 | ALDH1A1 440/4885SMN1; SMN2 4383/4885TP53 3913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.