Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | LTA4H | P09960 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | CASP7 | P55210 | 2/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL547394 | 0.73 | APP (0.46) | CYP2A6 | |
| SCHEMBL2965431 | 0.72 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL28581187 | 0.70 | NPC1 (0.43) | KDM4ENPC1RAB9AALDH1A1HSD17B10 | |
| SCHEMBL6992749 | 0.68 | CYP2A6 (0.38) | ALDH1A1HPGDMAPTLMNACYP2A6 | |
| SCHEMBL16291133 | 0.64 | L3MBTL1 (0.57) | KDM4ENPC1RAB9AL3MBTL1LTA4H | |
| SCHEMBL3545 | 0.64 | L3MBTL1 (0.57) | KDM4ENPC1RAB9AL3MBTL1LTA4H | |
| SCHEMBL218556 | 0.63 | GPR3 (0.35) | — | |
| SCHEMBL550941 | 0.63 | GPR3 (0.35) | KDM4ERAB9AALDH1A1HSD17B10HPGD | |
| SCHEMBL2775439 | 0.63 | GPR3 (0.35) | KDM4ERAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL4720558 | 0.63 | KDM4E (0.43) | KDM4ENPC1RAB9AL3MBTL1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6989446-B2 | Process for the preparation of 3-aryl-benzofuranones | CIBA SPECIALTY CHEMICALS CORP. (US) | 2006-01-24 | — | — | US | disclosed |
| US-20030018191-A1 | Reacting an aromatic carbonyl compound with carbon monoxide in presence of a metal catalyst | TINKL MICHAEL (DE) | 2003-01-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030018191-A1 | Reacting an aromatic carbonyl compound with carbon monoxide in presence of a metal catalyst | MT-CO2, CYC1, MT-CO1 | KDM4E 491/4885NPC1 2043/4885RAB9A 2722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.