Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19762859 | 0.97 | — | — | |
| Bromide SCHEMBL22034658 | 0.95 | LMNA (0.43) | CYP3A4SLC5A7DNM1MEN1LMNA | |
| Hydrochloric Acid SCHEMBL5990314 | 0.86 | DNM1 (0.35) | CYP3A4SLC5A7DNM1MEN1LMNA | |
| Hydrochloric Acid SCHEMBL4611856 | 0.84 | ALDH1A1 (0.32) | MEN1LMNAKMT2A | |
| SCHEMBL10756971 | 0.83 | DNM1 (0.37) | CYP3A4SLC5A7DNM1MEN1LMNA | |
| Hydrochloric Acid SCHEMBL5989564 | 0.82 | DNM1 (0.42) | DNM1MEN1LMNAKMT2A | |
| SCHEMBL4253271 | 0.81 | ALDH1A1 (0.33) | MEN1LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL4612119 | 0.79 | HTT (0.37) | DNM1MEN1LMNAKMT2A | |
| Bromide SCHEMBL4170067 | 0.77 | HTT (0.40) | DNM1MEN1LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL156326 | 0.74 | CYP3A4 (0.62) | CYP3A4SLC5A7DNM1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7030075-B2 | Organic activator | PROCTER & GAMBLE COMPANY (US) | 2006-04-18 | — | — | US | disclosed |
| US-20060074001-A1 | Organic activator | MIRACLE GREOGORY S | 2006-04-06 | — | — | US | disclosed |
| EP-1572631-A2 | ORGANIC ACTIVATOR | The Procter & Gamble Company (US) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004060856-A2 | ORGANIC ACTIVATOR | THE PROCTER & GAMBLE COMPANY (US) | 2004-07-22 | — | — | WO | disclosed |
| US-20040142844-A1 | bleach activators; N-hydroxyalkyl quaternary ammonium acetonitriles, e.g., 1-cyano-N,N-dimethyl-N-(3-hydroxypropyl)methanaminium chloride or quaternary ammonium acetonitrile inner salts, e.g., 5-carboxy-N,N-dimethyl-N-(cyanomethyl)-1-pentanaminium | THE PROCTER & GAMBLE COMPANY | 2004-07-22 | — | — | US | disclosed |