Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGO2 | Q9UKV8 | 1/20 | 1.00 |
| ▸ | C9 | P02748 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.44 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL976393 | 0.99 | AGO2 (0.97) | AGO2C9KDM4EALDH1A1HPGD | |
| SCHEMBL2833452 | 0.68 | KDM4E (0.62) | AGO2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1649282 | 0.68 | ALDH1A1 (0.62) | AGO2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9755165 | 0.68 | KDM4E (0.67) | AGO2C9KDM4EALDH1A1HPGD | |
| SCHEMBL14381820 | 0.67 | KDM4E (0.61) | AGO2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10370338 | 0.65 | KDM4E (0.62) | AGO2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11233617 | 0.64 | KDM4E (0.66) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL11217868 | 0.64 | KDM4E (0.66) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL8428483 | 0.63 | CA1 (0.58) | AGO2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL658651 | 0.63 | KDM4E (0.56) | AGO2KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200121697-A1 | METHODS FOR DIAGNOSING AND TREATING CACHEXIA | AURIN BIOTECH INC. (CA) | 2020-04-23 | — | — | US | claimed |
| EP-3630121-A1 | METHODS FOR DIAGNOSING AND TREATING CACHEXIA | Aurin Biotech Inc. (CA) | 2020-04-08 | — | — | EP | claimed |
| WO-2018218357-A1 | METHODS FOR DIAGNOSING AND TREATING CACHEXIA | AURIN BIOTECH INC. (CA) | 2018-12-06 | — | — | WO | claimed |
| US-20200121697-A1 | METHODS FOR DIAGNOSING AND TREATING CACHEXIA | AURIN BIOTECH INC. (CA) | 2020-04-23 | — | — | US | disclosed |
| EP-3630121-A1 | METHODS FOR DIAGNOSING AND TREATING CACHEXIA | Aurin Biotech Inc. (CA) | 2020-04-08 | — | — | EP | disclosed |
| US-20200064352-A1 | Specific GNAI:GIV Interaction Screening Assays, Methods and Compositions | UNIV CALIFORNIA (US) | 2020-02-27 | — | — | US | disclosed |
| WO-2018218357-A1 | METHODS FOR DIAGNOSING AND TREATING CACHEXIA | AURIN BIOTECH INC. (CA) | 2018-12-06 | — | — | WO | disclosed |
| WO-2012065139-A2 | ENTPD5 INHIBITORS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200064352-A1 | Specific GNAI:GIV Interaction Screening Assays, Methods and Compositions | GNAI1, GNAI3, GNAI2 | AGO2 4325/4885C9 2751/4885KDM4E 4725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.