SCHEMBL5996320

SCHEMBL5996320

Cc1cccc(C)c1C(=O)[PH](=O)CCC(=O)c1c(Cl)cc(Cl)cc1Cl

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.34
MRGPRX4 Q96LA9 1/20 0.33
FABP3 P05413 1/20 0.33
FABP4 P15090 1/20 0.33
TYK2 P29597 1/20 0.32
FEN1 P39748 1/20 0.32
THRB P10828 3/20 0.32
F2R P25116 1/20 0.32
KMT2A Q03164 2/20 0.31
NPSR1 Q6W5P4 2/20 0.31
MAPT P10636 2/20 0.31
UTS2R Q9UKP6 1/20 0.31
ELANE P08246 1/20 0.31
LMNA P02545 1/20 0.31
HTT P42858 1/20 0.31
PTGS2 P35354 1/20 0.31
ITGB1 P05556 2/20 0.31
ITGA4 P13612 2/20 0.31
ALDH1A1 P00352 2/20 0.31
ITGA2 P17301 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5996459 0.90 FEN1 (0.41) FABP3FABP4TYK2FEN1KMT2A
SCHEMBL5996625 0.88 RAPGEF4 (0.36) THRBKMT2AMAPTLMNAHTT
SCHEMBL5995871 0.84 ACLY (0.33) THRBKMT2A
SCHEMBL5996318 0.84 KMT2A (0.43) TYK2FEN1KMT2AMAPTLMNA
SCHEMBL5995801 0.83 CA12 (0.39) FABP4KMT2AITGB1ITGA4MEN1
SCHEMBL5997924 0.82 MAPT (0.36) FFAR1F2RKMT2AMAPTLMNA
SCHEMBL5997542 0.82 MAPT (0.36) FFAR1F2RKMT2AMAPTLMNA
SCHEMBL5995199 0.81 RAB9A (0.36) TYK2FEN1KMT2ANPSR1MAPT
SCHEMBL5995888 0.79 GABRA1 (0.34) F2RKMT2AMAPTHTTPTGS2
SCHEMBL5995848 0.78 ACHE (0.35) MRGPRX4THRBF2RMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7026017-B2 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-04-11 US disclosed
US-6969733-B2 Photoinitiators CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-11-29 US disclosed
US-6737549-B2 PHOTOINITIATORS FOR ACRYLATE COATINGS CIBA SPECIALTY CHEMICALS CORPORATION 2004-05-18 US disclosed
US-20030139485-A1 Photoinitiators WOLF JEAN-PIERRE (CH) 2003-07-24 US disclosed
US-20030130370-A1 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation WOLF JEAN-PIERRE (CH) 2003-07-10 US disclosed
US-20020026049-A1 Photoinitiators for acrylate coatings CIBA SPECIALTY CHEMICALS CORP. 2002-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030139485-A1 Photoinitiators DHCR24, NR1I3, CBR1 FFAR1 615/4885MRGPRX4 3110/4885FABP3 3788/4885
US-20030130370-A1 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation SMARCC1, ARPC5L, DHCR24 FFAR1 2131/4885MRGPRX4 2754/4885FABP3 4397/4885
US-20020026049-A1 Photoinitiators for acrylate coatings DHCR24, NR5A1, NR2C2 FFAR1 568/4885MRGPRX4 2582/4885FABP3 4336/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.