Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | CTSG | P08311 | 1/20 | 0.40 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27618946 | 0.80 | KMT2A (0.51) | ALOX5MGLLMAPTCYP1A2ADRB1 | |
| SCHEMBL10618445 | 0.77 | POLB (0.46) | ALOX5MAPTCYP1A2NPC1SMN1; SMN2 | |
| SCHEMBL20702773 | 0.76 | CA12 (0.42) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL20703098 | 0.72 | TUBB4A (0.37) | MAPTNPC1PDE4APDE4BPDE4C | |
| SCHEMBL15057788 | 0.72 | HDAC4 (0.46) | CYP1A2SMN1; SMN2RAB9A | |
| SCHEMBL27762341 | 0.72 | NPC1 (0.49) | ALOX5MGLLMAPTCYP1A2NPC1 | |
| SCHEMBL5997170 | 0.72 | MGLL (0.45) | MGLLMAPTCYP1A2SMN1; SMN2 | |
| SCHEMBL4662941 | 0.72 | MAPT (0.68) | MGLLMAPTCYP1A2SMN1; SMN2L3MBTL1 | |
| SCHEMBL25366082 | 0.71 | ALOX5 (0.55) | ALOX5MGLLMAPTCYP1A2NPC1 | |
| SCHEMBL30516650 | 0.71 | ALOX5 (0.55) | ALOX5MGLLMAPTCYP1A2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007047394-A2 | THIOTRIAZOLYL DERIVATIVES | EPIX DELAWARE, INC. (US) | 2007-04-26 | — | — | WO | disclosed |