Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3484826 | 0.88 | GAA (0.59) | GAAALDH1A1MAPK1MAPTLMNA | |
| SCHEMBL599787 | 0.88 | GAA (0.59) | GAAALDH1A1MAPK1MAPTLMNA | |
| SCHEMBL11796389 | 0.84 | ALDH1A1 (0.54) | TBXA2RALDH1A1MAPK1TDP1MAPT | |
| SCHEMBL8356647 | 0.82 | TDP1 (0.62) | PTGESTDP1MAPTCCR5 | |
| SCHEMBL4663012 | 0.82 | TDP1 (0.62) | PTGESTDP1MAPTCCR5 | |
| SCHEMBL5117215 | 0.80 | HTT (0.56) | GAAALDH1A1HSD11B1 | |
| SCHEMBL11184672 | 0.79 | CCR5 (0.56) | ALDH1A1PTGESTDP1HSD11B1MAPT | |
| SCHEMBL9840356 | 0.79 | MAPT (0.50) | GAATBXA2RALDH1A1MAPK1MAPT | |
| SCHEMBL11797446 | 0.79 | MAPK1 (0.54) | TBXA2RALDH1A1MAPK1TDP1HDAC3 | |
| SCHEMBL10246043 | 0.79 | GAA (0.62) | GAATDP1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4367092-A | DISCOLORATION INHIBITION | ROTO-FINISH COMPANY, INC. (US) | 1983-01-04 | — | — | US | claimed |
| US-9068137-B2 | Water-mixed metal working fluids containing ether pyrrolidone carboxylic acids | CLARIANT FINANCE (BVI) LIMITED (VG) | 2015-06-30 | — | — | US | disclosed |
| US-8759264-B2 | Water-based hydraulic fluids comprising dithio-di(aryl carbolic acids) | CLARIENT FINANCE (BVI) LIMITED (VG) | 2014-06-24 | — | — | US | disclosed |
| US-20120088706-A1 | WATER-MIXED METAL WORKING FLUIDS CONTAINING ETHER PYRROLIDONE CARBOXYLIC ACIDS | CLARIANT FINANCE (BVI) LIMITED (VG) | 2012-04-12 | — | — | US | disclosed |
| US-20120088705-A1 | POLYALKYLENE GLYCOL-BASED ETHER PYRROLIDONE CARBOXYLIC ACIDS, AND CONCENTRATES FOR THE PRODUCTION OF SYNTHETIC COOLING LUBRICANTS CONTAINING THE SAME | CLARIANT FINANCE (BVI) LIMITED (VG) | 2012-04-12 | — | — | US | disclosed |
| US-20120040875-A1 | Water-Based Hydraulic Fluids Comprising Dithio-Di(Aryl Carbolic Acids) | CLARIANT FINANCE (BVI) LIMITED (VG) | 2012-02-16 | — | — | US | disclosed |
| US-4911888-A | Salt containing phenyl ring | BASF AKTIENGESELLSCHAFT (DE) | 1990-03-27 | — | — | US | disclosed |
| US-4367092-A | DISCOLORATION INHIBITION | ROTO-FINISH COMPANY, INC. (US) | 1983-01-04 | — | — | US | disclosed |
| US-4367092-A | DISCOLORATION INHIBITION | ROTO-FINISH COMPANY, INC. (US) | 1983-01-04 | — | — | US | disclosed |
| US-4344862-A | Reaction products of sulfonamido-carboxylic acids or carboxamido-carboxylic acids with alkanolamines, and their use as low-foaming corrosion inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 1982-08-17 | — | — | US | disclosed |
| US-3992306-A | BIS-SULFONAMIDO-BIS-CARBOXYLIC ACID | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088705-A1 | POLYALKYLENE GLYCOL-BASED ETHER PYRROLIDONE CARBOXYLIC ACIDS, AND CONCENTRATES FOR THE PRODUCTION OF SYNTHETIC COOLING LUBRICANTS CONTAINING THE SAME | F12, ADH1A, ADH1C | GAA 2347/4885TBXA2R 3575/4885ALDH1A1 241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.