Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | MAOA | P21397 | 3/20 | 0.49 |
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.49 |
| ▸ | ALPG | P10696 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | CUL4A | Q13619 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6001557 | 0.77 | MAPT (0.67) | MAPTHPGDMAOAMAOBHTT | |
| SCHEMBL24091291 | 0.76 | MAPT (0.60) | MAPTHPGDMAOAMAOBHTT | |
| SCHEMBL14464230 | 0.71 | MAPT (0.46) | MAPTHPGDMAOAMAOBHTT | |
| SCHEMBL1000191 | 0.70 | MAPT (0.49) | MAPTHPGDMAOAMAOBHTT | |
| SCHEMBL8035971 | 0.68 | MAOA (0.57) | MAPTHPGDMAOAMAOBHTT | |
| SCHEMBL6001478 | 0.68 | MAOA (0.43) | MAPTHPGDMAOAMAOBHTT | |
| SCHEMBL6001543 | 0.67 | CUL4A (0.54) | MAPTHPGDMAOAMAOBHTT | |
| SCHEMBL6002101 | 0.67 | CUL4A (0.54) | MAPTHPGDMAOAMAOBHTT | |
| SCHEMBL8200836 | 0.67 | MAPT (0.53) | MAPTHPGDMAOAMAOBHTT | |
| SCHEMBL10397843 | 0.67 | MAPT (0.49) | MAPTHPGDMAOAMAOBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060234987-A1 | Neuroprotective benzo 1 3 oxathiol 2 ones | JAQUITH JAMES B | 2006-10-19 | — | — | US | disclosed |
| WO-2005012281-A1 | NEUROPROTECTIVE BENZO[1,3]OXATHOL-2-ONES | AEGERA THERAPEUTICS INC. (CA) | 2005-02-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060234987-A1 | Neuroprotective benzo 1 3 oxathiol 2 ones | NLN, SMN1; SMN2, TXN2 | MAPT 204/4885HPGD 1281/4885MAOA 1236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.