Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.51 |
| ▸ | CLK1 | P49759 | 8/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.50 |
| ▸ | DYRK1B | Q9Y463 | 4/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23041058 | 0.90 | PDGFRB (0.62) | CNR2CNR1MAPTALDH1A1KDM4E | |
| SCHEMBL6000839 | 0.85 | CYP1A2 (0.54) | ALDH1A1KDM4EL3MBTL1CLK1DYRK1A | |
| SCHEMBL6001679 | 0.85 | DYRK1A (0.67) | CNR2CNR1MAPTALDH1A1KDM4E | |
| SCHEMBL6001641 | 0.79 | POLB (0.50) | MAPTALDH1A1LMNATDP1L3MBTL1 | |
| SCHEMBL9431835 | 0.77 | ALDH1A1 (0.60) | MAPTALDH1A1KDM4EHPGDL3MBTL1 | |
| SCHEMBL23041054 | 0.76 | DYRK1A (0.68) | CNR2CNR1PDGFRBPDGFRACLK1 | |
| SCHEMBL5999605 | 0.75 | DYRK1A (0.59) | CNR2CNR1CLK1DYRK1ADYRK1B | |
| SCHEMBL6790338 | 0.74 | MAPT (0.69) | MAPTALDH1A1LMNAHPGDTDP1 | |
| SCHEMBL30298102 | 0.74 | TUBB4A (0.51) | CNR2CNR1MAPTALDH1A1PDGFRB | |
| SCHEMBL6557518 | 0.73 | RAB9A (0.65) | MAPTALDH1A1KDM4ELMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060142271-A1 | Novel lapacho compounds and methods of use thereof | MUNSTER, UNIVERSITY OF (DE) | 2006-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142271-A1 | Novel lapacho compounds and methods of use thereof | XIAP, PIN1, NQO1 | CNR2 3456/4885CNR1 2985/4885MAPT 3494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.