Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6002146 | 0.96 | HTR1A (0.45) | RAD52SRD5A1HTR1AHTR2CDRD3 | |
| SCHEMBL7684611 | 0.92 | HTR1A (0.43) | RAD52SRD5A1HTR1AHTR2CDRD3 | |
| SCHEMBL6002172 | 0.84 | OPRM1 (0.51) | RAD52HTR1AHTR2CDRD3 | |
| SCHEMBL6002219 | 0.79 | CHRNA7 (0.66) | HTR1AHTR2CDRD3 | |
| SCHEMBL6001612 | 0.78 | DRD2 (0.49) | RAD52SRD5A1HTR2CDRD3 | |
| SCHEMBL7684443 | 0.77 | HTR2C (0.44) | HTR2C | |
| SCHEMBL6405877 | 0.77 | DRD2 (0.44) | HTR1AHTR2CDRD3 | |
| SCHEMBL7678362 | 0.76 | SLC6A2 (0.41) | HTR2C | |
| SCHEMBL7677541 | 0.75 | CHRNA7 (0.42) | SRD5A1 | |
| SCHEMBL6001969 | 0.74 | CHRNA7 (0.68) | HTR1AHTR2CDRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060166984-A1 | Amino substituted benzo(hetero)cyclic derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2006-07-27 | — | — | US | disclosed |
| EP-1603395-A2 | AMINO SUBSTITUTED BENZO(HETERO)CYCLIC DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2005-12-14 | — | — | EP | disclosed |
| WO-2004080170-A2 | AMINO SUBSTITUTED BENZO(HETERO)CYCLIC DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2004-09-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060166984-A1 | Amino substituted benzo(hetero)cyclic derivatives | CBR3, L3MBTL3, BRS3 | RAD52 424/4885SRD5A1 3930/4885HTR1A 2209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.