Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PARG | Q86W56 | 1/20 | 0.31 |
| ▸ | HK1 | P19367 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.30 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.30 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.30 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6001985 | 0.91 | PTGDR2 (0.36) | ALDH1A1HPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6002331 | 0.85 | MEN1 (0.42) | CACNA1BALDH1A1MAPTHTTNPSR1 | |
| SCHEMBL6001840 | 0.83 | CACNA1B (0.40) | CACNA1BALDH1A1MAPTTP53TDP1 | |
| SCHEMBL6001804 | 0.78 | L3MBTL1 (0.34) | — | |
| SCHEMBL6001962 | 0.75 | POLB (0.48) | ALDH1A1MAPTHPGDHTTNPSR1 | |
| SCHEMBL6002334 | 0.72 | SMN1; SMN2 (0.39) | ALDH1A1MAPTHPGDGAAMEN1 | |
| SCHEMBL6002238 | 0.70 | CACNA1B (0.40) | CACNA1BALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL6002281 | 0.69 | CCR2 (0.41) | — | |
| SCHEMBL6000254 | 0.67 | MEN1 (0.41) | CACNA1BALDH1A1MAPTKDM4EGAA | |
| SCHEMBL6001790 | 0.66 | CACNA1B (0.44) | CACNA1BALDH1A1KDM4EGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212296-B9 | PHOSPHATE MIMICS AND METHODS OF TREATMENT USING PHOSPHATASE INHIBITORS | SUGEN INC (US) | 2006-05-10 | — | — | EP | claimed |
| EP-1212296-B1 | PHOSPHATE MIMICS AND METHODS OF TREATMENT USING PHOSPHATASE INHIBITORS | SUGEN INC (US) | 2005-11-09 | — | — | EP | claimed |