Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6001797 | 0.91 | CACNA1B (0.38) | ALDH1A1HPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6001804 | 0.87 | L3MBTL1 (0.34) | PTGDR2AKR1B1PLA2G4AL3MBTL1 | |
| SCHEMBL6001962 | 0.84 | POLB (0.48) | ALDH1A1HPGDTSHRSMN1; SMN2POLB | |
| SCHEMBL6002334 | 0.81 | SMN1; SMN2 (0.39) | PTGDR2AKR1B1ALDH1A1HPGDTSHR | |
| SCHEMBL6002281 | 0.78 | CCR2 (0.41) | PLA2G4AL3MBTL1 | |
| SCHEMBL6002331 | 0.74 | MEN1 (0.42) | ALDH1A1TSHRSMN1; SMN2POLBLMNA | |
| SCHEMBL6001840 | 0.72 | CACNA1B (0.40) | ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6002268 | 0.68 | MAPK1 (0.38) | PTGDR2SMN1; SMN2L3MBTL1 | |
| SCHEMBL9239665 | 0.67 | TDP1 (0.48) | ALDH1A1HPGDTSHRLMNAL3MBTL1 | |
| SCHEMBL6002237 | 0.66 | KDM4E (0.58) | ALDH1A1HPGDSMN1; SMN2LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212296-B9 | PHOSPHATE MIMICS AND METHODS OF TREATMENT USING PHOSPHATASE INHIBITORS | SUGEN INC (US) | 2006-05-10 | — | — | EP | claimed |
| EP-1212296-B1 | PHOSPHATE MIMICS AND METHODS OF TREATMENT USING PHOSPHATASE INHIBITORS | SUGEN INC (US) | 2005-11-09 | — | — | EP | claimed |