Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6002281 | 0.83 | CCR2 (0.41) | L3MBTL1PLA2G4A | |
| SCHEMBL6002268 | 0.79 | MAPK1 (0.38) | L3MBTL1PTGDR2 | |
| SCHEMBL6001797 | 0.78 | CACNA1B (0.38) | — | |
| SCHEMBL6002238 | 0.70 | CACNA1B (0.40) | — | |
| SCHEMBL6002331 | 0.69 | MEN1 (0.42) | L3MBTL1 | |
| SCHEMBL6002334 | 0.68 | SMN1; SMN2 (0.39) | PTGDR2AKR1B1 | |
| SCHEMBL6002292 | 0.65 | SERPINE1 (0.48) | — | |
| SCHEMBL6002233 | 0.63 | ECE1 (0.43) | — | |
| SCHEMBL6001713 | 0.61 | SERPINE1 (0.49) | — | |
| SCHEMBL9243077 | 0.61 | CCR2 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212296-B9 | PHOSPHATE MIMICS AND METHODS OF TREATMENT USING PHOSPHATASE INHIBITORS | SUGEN INC (US) | 2006-05-10 | — | — | EP | claimed |
| EP-1212296-B1 | PHOSPHATE MIMICS AND METHODS OF TREATMENT USING PHOSPHATASE INHIBITORS | SUGEN INC (US) | 2005-11-09 | — | — | EP | claimed |