Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23223243 | 0.79 | SLC6A3 (0.43) | SLC6A3SLC6A2DAOSMN1; SMN2 | |
| SCHEMBL28752736 | 0.79 | LMNA (0.47) | SLC6A3SLC6A2TAAR1TDP1 | |
| SCHEMBL9389496 | 0.73 | SLC6A3 (0.49) | SLC6A3SLC6A2TDP1 | |
| SCHEMBL9024874 | 0.72 | HPGD (0.54) | ABL1TAAR1SMN1; SMN2 | |
| SCHEMBL3301625 | 0.71 | TAAR1 (0.59) | TAAR1DAOAR | |
| SCHEMBL765420 | 0.70 | SLC6A3 (0.51) | SLC6A3ABL1SLC6A2TP53SMN1; SMN2 | |
| SCHEMBL16051513 | 0.69 | ALDH1A1 (0.44) | ABL1SMN1; SMN2 | |
| SCHEMBL963467 | 0.69 | EPHX2 (0.49) | ABL1TAAR1ADORA2AADORA1TP53 | |
| SCHEMBL2091427 | 0.68 | HDAC3 (0.34) | SLC6A3SLC6A2TDP1 | |
| SCHEMBL4758082 | 0.68 | ADRA1D (0.51) | SLC6A3TAAR1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |