Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 3/20 | 0.46 |
| ▸ | AR | P10275 | 2/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NCF1 | P14598 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1331903 | 0.79 | CRHBP (0.47) | PRKDCARHPGDNCF1ALDH1A1 | |
| SCHEMBL3080094 | 0.77 | NCF1 (0.67) | ARCTSBHPGDNCF1ALDH1A1 | |
| SCHEMBL7491687 | 0.77 | NCF1 (0.67) | ARCTSBHPGDNCF1ALDH1A1 | |
| SCHEMBL29139355 | 0.76 | RAB9A (0.47) | PRKDCARCTSBHPGDNCF1 | |
| SCHEMBL28401632 | 0.76 | ERN1 (0.50) | PRKDCARCTSBHPGDNCF1 | |
| SCHEMBL6002813 | 0.75 | PRKDC (0.46) | PRKDCHPGDALDH1A1L3MBTL1KDM4E | |
| SCHEMBL1876619 | 0.75 | NCF1 (0.69) | ARCTSBHPGDNCF1ALDH1A1 | |
| SCHEMBL30719030 | 0.74 | L3MBTL1 (0.49) | PRKDCARCTSBHPGDNCF1 | |
| SCHEMBL20436315 | 0.73 | KEAP1 (0.50) | PRKDCARHPGDNCF1ALDH1A1 | |
| Lithium SCHEMBL31260768 | 0.73 | NCF1 (0.67) | ARCTSBHPGDNCF1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |