Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 9/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6003943 | 0.82 | TP53 (0.53) | TP53ABL1NPC1RAB9AL3MBTL1 | |
| SCHEMBL6002626 | 0.75 | TP53 (0.52) | TP53ALDH1A1ABL1NPC1RAB9A | |
| SCHEMBL6003781 | 0.73 | NPY5R (0.49) | TP53ALDH1A1 | |
| SCHEMBL6003902 | 0.73 | ALOX15 (0.63) | ALOX15TP53ALDH1A1ABL1NPC1 | |
| SCHEMBL3989236 | 0.73 | ALOX15 (0.94) | ALOX15ALDH1A1NPC1RAB9A | |
| SCHEMBL2907641 | 0.72 | ALOX15 (1.00) | ALOX15ALDH1A1NPC1RAB9AEPHX2 | |
| SCHEMBL6454874 | 0.69 | ALOX15 (0.57) | ALOX15 | |
| SCHEMBL6004365 | 0.67 | ALOX15 (0.61) | ALOX15TP53ALDH1A1NPC1RAB9A | |
| SCHEMBL26697230 | 0.67 | EPHX2 (0.64) | TP53NPC1RAB9AEPHX2 | |
| SCHEMBL11012705 | 0.67 | TDP1 (0.72) | ABL1NPC1RAB9AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060183780-A1 | Pyrazole compounds useful in the treatment of inflammation | BIOLIPOX AB (SE) | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183780-A1 | Pyrazole compounds useful in the treatment of inflammation | ALOX15, ALOX12, ALOX15B | ALOX15 1/4885TP53 2001/4885ALDH1A1 763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.