Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.46 |
| ▸ | ABL1 | P00519 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6002665 | 0.82 | ALOX15 (0.64) | TP53ABL1RAB9ANPC1L3MBTL1 | |
| SCHEMBL6002626 | 0.80 | TP53 (0.52) | TP53HTTSMN1; SMN2ABL1KMT2A | |
| SCHEMBL6003781 | 0.72 | NPY5R (0.49) | TP53TDP1HTTSMN1; SMN2KMT2A | |
| SCHEMBL17448399 | 0.71 | SMN1; SMN2 (0.71) | TP53HTTSMN1; SMN2ABL1KMT2A | |
| SCHEMBL10795715 | 0.69 | TDP1 (0.75) | TP53TDP1PTGS2HTTSMN1; SMN2 | |
| SCHEMBL6716560 | 0.68 | TDP1 (0.62) | TDP1PTGS2HTTSMN1; SMN2ABL1 | |
| SCHEMBL6683080 | 0.67 | TDP1 (0.56) | TDP1PTGS2HTTSMN1; SMN2CHRNA7 | |
| SCHEMBL29699885 | 0.67 | TP53 (0.52) | TP53HTTSMN1; SMN2ABL1KMT2A | |
| SCHEMBL2533682 | 0.67 | NPC1 (0.71) | TP53HTTSMN1; SMN2ABL1KMT2A | |
| SCHEMBL30904871 | 0.67 | NPC1 (0.71) | TP53HTTSMN1; SMN2ABL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060183780-A1 | Pyrazole compounds useful in the treatment of inflammation | BIOLIPOX AB (SE) | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183780-A1 | Pyrazole compounds useful in the treatment of inflammation | ALOX15, ALOX12, ALOX15B | TP53 2001/4885TDP1 2603/4885PTGS2 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.