Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 9/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 9/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15412644 | 0.86 | ALOX5 (0.41) | ALOX5PPARGPPARACHRNB2CHRNB4 | |
| SCHEMBL14713063 | 0.83 | ALOX5 (0.41) | PTGS1ALOX5PPARGPPARACHRNB2 | |
| SCHEMBL27275524 | 0.82 | ALOX5 (0.41) | PTGS1ALOX5PPARGPPARACHRNB2 | |
| SCHEMBL113145 | 0.81 | ALOX5 (0.44) | ALOX5PPARGPPARACHRNB2CHRNB4 | |
| SCHEMBL10683115 | 0.81 | CHRNB2 (0.43) | ALOX5CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL27510765 | 0.81 | ALOX5 (0.44) | AKR1C3PTGS1ALOX5PPARGPPARA | |
| SCHEMBL11362145 | 0.81 | CHRNB2 (0.43) | ALOX5CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL1095592 | 0.81 | ALOX5 (0.44) | PTGS1ALOX5PPARGPPARACHRNB2 | |
| Hydrochloric Acid SCHEMBL111897 | 0.80 | ALOX5 (0.42) | ALOX5PPARGPPARACHRNB2CHRNB4 | |
| SCHEMBL1494183 | 0.80 | ALOX5 (0.40) | ALOX5CHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11819833-B2 | Conducting polymer and carbon nitride based nanocomposite photocatalyst for degradation of aqueous organic pollutants | Najran University (SA) | 2023-11-21 | — | — | US | disclosed |
| US-20230330644-A1 | CONDUCTING POLYMER AND CARBON NITRIDE BASED NANOCOMPOSITE PHOTOCATALYST FOR DEGRADATION OF AQUEOUS ORGANIC POLLUTANTS | Najran University (SA) | 2023-10-19 | — | — | US | disclosed |
| US-11713397-B1 | Composition for forming corrosion resistant composite coating | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2023-08-01 | — | — | US | disclosed |
| US-11530327-B1 | Saltwater corrosion-resistant composite coating | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2022-12-20 | — | — | US | disclosed |
| US-11447645-B1 | Saltwater corrosion resistant hybrid composite | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2022-09-20 | — | — | US | disclosed |
| EP-4041249-A1 | COMPOSITIONS AND METHODS FOR IN VIVO SYNTHESIS OF UNNATURAL POLYPEPTIDES | The Scripps Research Institute (US) | 2022-08-17 | — | — | EP | disclosed |
| WO-2022170108-A1 | PEPTIDOMIMETIC MACROCYCLES AND USES THEREOF IN PREVENTION OF RADIATION INJURY | AILERON THERAPEUTICS, INC. (US) | 2022-08-11 | — | — | WO | disclosed |
| US-10626087-B2 | Indoline and tetrahydroquinoline sulfonyl inhibitors of dimetalloenzymes and use of the same | LOYOLA UNIVERSITY OF CHICAGO (US) | 2020-04-21 | — | — | US | disclosed |
| US-20180170898-A1 | BETA- AND GAMMA-AMINO-ISOQUINOLINE AMIDE COMPOUNDS AND SUBSTITUTED BENZAMIDE COMPOUNDS | ALCON INC. (CH) | 2018-06-21 | — | — | US | disclosed |
| US-9884840-B2 | Beta- and gamma-amino-isoquinoline amide compounds and substituted benzamide compounds | AERIE PHARMACEUTICALS, INC. (US) | 2018-02-06 | — | — | US | disclosed |
| US-5532025-A | Corrosion inhibiting compositions | ZIPPERLING KESSLER & CO. (GMBH & CO.) (DE) | 1996-07-02 | — | — | US | disclosed |
| EP-0712336-A1 | CORROSION INHIBITING MULTILAYER COATING | MONSANTO COMPANY (US) | 1996-05-22 | — | — | EP | disclosed |
| CN-1121074-A | Novel N-pyridyl carboxamides and derivatives, processes for their preparation and the pharmaceutical compositions which contain them | ADIR (FR) | 1996-04-24 | — | — | CN | disclosed |
| WO-1995003136-A1 | CORROSION INHIBITING MULTILAYER COATING | MONSANTO COMPANY (US) | 1995-02-02 | — | — | WO | disclosed |
| CN-1097752-A | Benzocyclohepta alkene, benzoxepines and benzo thia | MERCK PATENT GMBH (DE) | 1995-01-25 | — | — | CN | disclosed |
| US-5314910-A | 2-Heteroaromatic alkanoate esters useful as inhibitors of human leukocyte or neutrophil elastase | CORTECH INC. (US) | 1994-05-24 | — | — | US | disclosed |
| US-5240956-A | Phenyl 2-heteroaromatic-alkanoates, elastase inhibitors | CORTECH, INC. (US) | 1993-08-31 | — | — | US | disclosed |
| EP-0484949-A2 | Ester inhibitors | CORTECH, INC. (US) | 1992-05-13 | — | — | EP | disclosed |
| EP-0221806-B1 | SUBSTITUTED THIOPHENE-2-SULFANOMIDE AND ANTIGLAUCOMA COMPOSITIONS CONTAINING THEM | MERCK & CO. INC. (US) | 1990-01-10 | — | — | EP | disclosed |
| EP-0221806-A1 | Substituted thiophene-2-sulfanomide and antiglaucoma compositions containing them | MERCK & CO. INC. (US) | 1987-05-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10626087-B2 | Indoline and tetrahydroquinoline sulfonyl inhibitors of dimetalloenzymes and use of the same | MGAM, INMT, NNMT | AKR1C3 3613/4885AKR1C2 2575/4885AKR1C1 2398/4885 |
| US-20180170898-A1 | BETA- AND GAMMA-AMINO-ISOQUINOLINE AMIDE COMPOUNDS AND SUBSTITUTED BENZAMIDE COMPOUNDS | PRKCQ, UACA, BCAT2 | AKR1C3 2535/4885AKR1C2 1631/4885AKR1C1 1661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.