Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 4/20 | 0.38 |
| ▸ | MAOB | P27338 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5282506 | 0.87 | MAOB (0.43) | TSHRMAOAMAOBCALM1ALDH1A1 | |
| SCHEMBL5247853 | 0.80 | TDP1 (0.45) | TSHRTDP1MAOAMAOBGAA | |
| SCHEMBL6002827 | 0.79 | ALDH1A1 (0.39) | TDP1MAOAMAOBLMNACALM1 | |
| SCHEMBL10967375 | 0.79 | MAOA (0.38) | TSHRMAOAMAOBCALM1ALDH1A1 | |
| SCHEMBL5280214 | 0.79 | TP53 (0.41) | TSHRMAOAMAOBCALM1ALDH1A1 | |
| SCHEMBL5275325 | 0.76 | MMP2 (0.38) | MAOAMAOBLMNAGAACALM1 | |
| SCHEMBL5279760 | 0.75 | SLC6A2 (0.35) | TSHRMAOAMAOBLMNAHPGD | |
| SCHEMBL5278439 | 0.75 | TAAR1 (0.35) | MAOAMAOBALDH1A1TRPA1 | |
| SCHEMBL5246710 | 0.74 | MAPT (0.43) | TDP1MAOAMAOBCES1 | |
| SCHEMBL3034490 | 0.74 | MAOA (0.40) | TSHRTDP1MAOAMAOBCALM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |