Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.38 |
| ▸ | MAOB | P27338 | 4/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5282506 | 0.87 | MAOB (0.43) | MAOAMAOBCALM1KDM1ATSHR | |
| SCHEMBL6002831 | 0.79 | TSHR (0.41) | MAOAMAOBCALM1KDM1ANOS2 | |
| SCHEMBL5280214 | 0.79 | TP53 (0.41) | MAOAMAOBCALM1KDM1ATSHR | |
| SCHEMBL6002827 | 0.79 | ALDH1A1 (0.39) | MAOAMAOBCALM1LOXL2ALDH1A1 | |
| SCHEMBL5275325 | 0.76 | MMP2 (0.38) | MAOAMAOBCALM1MEN1KMT2A | |
| SCHEMBL5278439 | 0.75 | TAAR1 (0.35) | MAOAMAOBSIGMAR1TP53TRPA1 | |
| SCHEMBL5279760 | 0.75 | SLC6A2 (0.35) | MAOAMAOBCYP19A1TSHRTP53 | |
| SCHEMBL5274344 | 0.74 | MAOA (0.40) | MAOAMAOBCYP19A1CALM1MEN1 | |
| SCHEMBL5282068 | 0.72 | MMP2 (0.49) | MEN1KMT2ASIGMAR1TP53 | |
| SCHEMBL5274739 | 0.71 | MMP2 (0.51) | MEN1KMT2ASIGMAR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0135814-A1 | 1-(1H-tetrazol-5-ylalkoxy)-2-azetidinones | E.R. Squibb & Sons, Inc. (US) | 1985-04-03 | — | — | EP | disclosed |