Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | STAT1 | P42224 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.32 |
| ▸ | ATP4A | P20648 | 1/20 | 0.32 |
| ▸ | ATP4B | P51164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11996622 | 0.74 | ALDH1A1 (0.35) | ALDH1A1MAPTTSHR | |
| SCHEMBL13034536 | 0.73 | KDM4E (0.40) | MAPT | |
| SCHEMBL11994166 | 0.71 | GPR84 (0.43) | GPR84SOAT1ALDH1A1MAPTNPSR1 | |
| SCHEMBL8403092 | 0.70 | GPR84 (0.49) | GPR84SOAT1ALDH1A1MAPTNPC1 | |
| SCHEMBL5167355 | 0.68 | CYP17A1 (0.49) | CYP17A1 | |
| SCHEMBL536902 | 0.67 | POLB (0.45) | ALDH1A1MAPT | |
| SCHEMBL28814006 | 0.67 | NPC1 (0.35) | SOAT1ALDH1A1MAPTNPC1STAT1 | |
| SCHEMBL23072120 | 0.66 | ALDH1A1 (0.50) | ALDH1A1MAPTTSHRATP4AATP4B | |
| SCHEMBL6002435 | 0.65 | ALOX5 (0.45) | ALDH1A1NPC1RAB9ATSHR | |
| SCHEMBL6003294 | 0.65 | ATP4A (0.43) | ALDH1A1NPC1RAB9AATP4AATP4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |