Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6002607 | 0.86 | ALOX15 (0.65) | ALOX15HIF1AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6003857 | 0.81 | ALOX15 (0.69) | ALOX15MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL6004808 | 0.78 | ALOX15 (0.56) | ALOX15MEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL2907641 | 0.75 | ALOX15 (1.00) | ALOX15KMT2ALMNAEPHX2 | |
| SCHEMBL6004365 | 0.74 | ALOX15 (0.61) | ALOX15KMT2ALMNASMN1; SMN2ASAH1 | |
| SCHEMBL3989236 | 0.72 | ALOX15 (0.94) | ALOX15KMT2ALMNA | |
| SCHEMBL6004189 | 0.71 | ALOX15 (0.66) | ALOX15MEN1KMT2ALMNAHTT | |
| SCHEMBL13577932 | 0.71 | MLYCD (0.73) | MEN1KMT2ALMNAHTTSMN1; SMN2 | |
| SCHEMBL31278057 | 0.70 | HIF1A (0.57) | ALOX15HIF1AMEN1KMT2ALMNA | |
| SCHEMBL28929298 | 0.70 | MLYCD (0.76) | MEN1KMT2ASMN1; SMN2EPHX2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060183780-A1 | Pyrazole compounds useful in the treatment of inflammation | BIOLIPOX AB (SE) | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183780-A1 | Pyrazole compounds useful in the treatment of inflammation | ALOX15, ALOX12, ALOX15B | ALOX15 1/4885HIF1A 1580/4885MEN1 4278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.