Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6004193 | 0.87 | ALOX15 (0.73) | ALOX15MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL2907641 | 0.82 | ALOX15 (1.00) | ALOX15KMT2ANPC1RAB9ALMNA | |
| SCHEMBL6003478 | 0.81 | ALOX15 (0.60) | ALOX15MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL6004808 | 0.80 | ALOX15 (0.56) | ALOX15MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL3989236 | 0.78 | ALOX15 (0.94) | ALOX15KMT2ANPC1RAB9ALMNA | |
| SCHEMBL6004044 | 0.73 | ALOX15 (0.74) | ALOX15MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL6004365 | 0.71 | ALOX15 (0.61) | ALOX15KMT2ASMN1; SMN2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL31277222 | 0.70 | KMT2A (0.56) | ALOX15MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL31277895 | 0.70 | MEN1 (0.58) | ALOX15MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL6004374 | 0.69 | ALOX15 (0.61) | ALOX15MEN1KMT2ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060183780-A1 | Pyrazole compounds useful in the treatment of inflammation | BIOLIPOX AB (SE) | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183780-A1 | Pyrazole compounds useful in the treatment of inflammation | ALOX15, ALOX12, ALOX15B | ALOX15 1/4885MEN1 4278/4885KMT2A 4358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.