Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of 2-Pentanol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Pentanol SCHEMBL8093913 | 0.97 | CHRM1 (0.46) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| Methacrylic Acid SCHEMBL15821451 | 0.85 | CHRM1 (0.41) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| Methacrylic Acid SCHEMBL2551832 | 0.85 | CHRM1 (0.41) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| 2-Pentanol SCHEMBL469224 | 0.85 | — | — | |
| 2-Pentanol SCHEMBL469268 | 0.85 | — | — | |
| 2-Pentanol SCHEMBL17511847 | 0.85 | TSHR (0.53) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| 2-Pentanol SCHEMBL14956 | 0.85 | — | — | |
| 2-Hexanol SCHEMBL14916700 | 0.84 | CA2 (0.48) | GPR84FFAR1 | |
| 2-Pentanol SCHEMBL16093990 | 0.82 | ALDH1A1 (0.41) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| 2-Heptanol SCHEMBL21056374 | 0.82 | GPR84 (0.56) | NFKB1GPR84FFAR1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025046316-A1 | METHOD FOR PROCESSING CACAO PRODUCTS WITH IMPROVED FLAVOUR, AROMA AND RHEOLOGY | SUCESORES DE JOSE JESUS RESTREPO & CIA. S.A. CASA LUKER S.A. (CO) | 2025-03-06 | — | — | WO | claimed |
| US-20240361292-A1 | METHOD FOR ASSESSING RIPENESS OF FRUIT AND SYSTEM FOR ASSESSING RIPENESS OF FRUIT | PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) | 2024-10-31 | — | — | US | claimed |
| CN-117795337-A | Method and system for judging maturity of fruit | 松下知识产权经营株式会社 | 2024-03-29 | — | — | CN | claimed |
| WO-2023032853-A1 | METHOD FOR ASSESSING RIPENESS OF FRUIT AND SYSTEM FOR ASSESSING RIPENESS OF FRUIT | パナソニックＩＰマネジメント株式会社 | 2023-03-09 | — | — | WO | claimed |
| US-8647687-B2 | Isoamyl acetate for weight management | NESTEC S.A. (CH) | 2014-02-11 | — | — | US | claimed |
| EP-2143342-B1 | Aroma compounds for weight management | NESTEC SA (CH) | 2013-02-27 | — | — | EP | claimed |
| US-12527333-B2 | Foodstuff products, ingredients, processes and uses | SOCIETE DES PRODUITS NESTLE S.A. (CH) | 2026-01-20 | — | — | US | disclosed |
| EP-3723494-B1 | FOODSTUFF PRODUCTS, INGREDIENTS, PROCESSES AND USES | NESTLE SA (CH) | 2025-09-17 | — | — | EP | disclosed |
| EP-3498102-B1 | FOODSTUFF PRODUCTS, INGREDIENTS, PROCESSES AND USES | NESTLE SA (CH) | 2025-09-17 | — | — | EP | disclosed |
| EP-3824738-B1 | FOODSTUFF PRODUCTS, INGREDIENTS, PROCESSES AND USES | NESTLE SA (CH) | 2025-09-17 | — | — | EP | disclosed |
| WO-2025046316-A1 | METHOD FOR PROCESSING CACAO PRODUCTS WITH IMPROVED FLAVOUR, AROMA AND RHEOLOGY | SUCESORES DE JOSE JESUS RESTREPO & CIA. S.A. CASA LUKER S.A. (CO) | 2025-03-06 | — | — | WO | disclosed |
| US-20240361292-A1 | METHOD FOR ASSESSING RIPENESS OF FRUIT AND SYSTEM FOR ASSESSING RIPENESS OF FRUIT | PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) | 2024-10-31 | — | — | US | disclosed |
| US-12063945-B2 | Chocolate products, ingredients, processes and uses | SOCIETE DES PRODUITS NESTLE S.A. (CH) | 2024-08-20 | — | — | US | disclosed |
| EP-2309877-B1 | ISOAMYL ACETATE FOR WEIGHT MANAGEMENT | NESTEC SA (CH) | 2013-04-24 | — | — | EP | disclosed |
| EP-2143342-B1 | Aroma compounds for weight management | NESTEC SA (CH) | 2013-02-27 | — | — | EP | disclosed |
| US-20120040046-A1 | ISOAMYL ACETATE FOR WEIGHT MANAGEMENT | NESTEC S.A. (CH) | 2012-02-16 | — | — | US | disclosed |
| EP-2309877-A1 | ISOAMYL ACETATE FOR WEIGHT MANAGEMENT | Nestec S.A. (CH) | 2011-04-20 | — | — | EP | disclosed |
| WO-2010003997-A1 | ISOAMYL ACETATE FOR WEIGHT MANAGEMENT | NESTEC S.A. (CH) | 2010-01-14 | — | — | WO | disclosed |
| EP-2143342-A1 | Aroma compounds for weight management | NESTEC S.A. (CH) | 2010-01-13 | — | — | EP | disclosed |
| US-4479962-A | CARDIOTONIC AGENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1984-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12527333-B2 | Foodstuff products, ingredients, processes and uses | TREH, LCT, ALPP | CHRM1 3357/4885AKR1A1 2965/4885CHRM3 4226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.