Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6003427 | 0.84 | MAPT (0.40) | GPBAR1RAB9ANPC1KMT2AALDH1A1 | |
| SCHEMBL6002581 | 0.73 | MGLL (0.41) | ALOX15GPBAR1RAB9ANPC1KMT2A | |
| SCHEMBL162022 | 0.70 | ALOX15 (0.47) | ALOX15BCHEKMT2AHTTTSHR | |
| SCHEMBL3989236 | 0.69 | ALOX15 (0.94) | ALOX15RAB9ANPC1KMT2AF2 | |
| SCHEMBL6003857 | 0.67 | ALOX15 (0.69) | ALOX15RAB9ANPC1KMT2ATSHR | |
| SCHEMBL2907641 | 0.67 | ALOX15 (1.00) | ALOX15RAB9ANPC1KMT2AF2 | |
| SCHEMBL11784631 | 0.66 | HPGD (0.54) | HPGDRAB9ANPC1ALDH1A1HTT | |
| SCHEMBL10573755 | 0.66 | HPGD (0.50) | HPGDRAB9ANPC1KMT2AALDH1A1 | |
| SCHEMBL31453167 | 0.64 | GPBAR1 (0.47) | GPBAR1KMT2A | |
| SCHEMBL23723514 | 0.62 | HPGD (0.39) | HPGDGPBAR1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060183780-A1 | Pyrazole compounds useful in the treatment of inflammation | BIOLIPOX AB (SE) | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183780-A1 | Pyrazole compounds useful in the treatment of inflammation | ALOX15, ALOX12, ALOX15B | ALOX15 1/4885HPGD 68/4885GPBAR1 890/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.