Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.43 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.43 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.43 |
| ▸ | STK10 | O94804 | 2/20 | 0.43 |
| ▸ | SLK | Q9H2G2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | WEE1 | P30291 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12459108 | 0.83 | GSK3B (0.42) | GSK3BCYP2A6CYP2B6CYP2E1STK10 | |
| SCHEMBL19216926 | 0.75 | PRKCB (0.48) | STK10SLKMAPTCHEK1WEE1 | |
| SCHEMBL8161280 | 0.74 | CCNE2 (0.72) | GSK3B | |
| SCHEMBL8980802 | 0.71 | CHEK1 (0.44) | GSK3BCYP2A6CYP2B6CYP2E1STK10 | |
| SCHEMBL15731559 | 0.71 | CYP2A6 (0.42) | CYP2A6CYP2B6CYP2E1PTPRCPTGS2 | |
| Formaldehyde SCHEMBL28680174 | 0.69 | CYP2A6 (0.62) | CYP2A6CYP2B6CYP2E1PTPRCKCNH2 | |
| SCHEMBL12393918 | 0.68 | GSK3B (0.33) | GSK3BSTK10SLKPIM1 | |
| SCHEMBL4180952 | 0.66 | CES1 (0.50) | GSK3BCYP2A6CYP2B6CYP2E1STK10 | |
| SCHEMBL27989815 | 0.66 | CYP2A6 (0.74) | GSK3BCYP2A6CYP2B6CYP2E1PTPRC | |
| SCHEMBL3966035 | 0.66 | GSK3B (0.40) | GSK3BCYP2A6CYP2B6CYP2E1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111315762-B | Optically controlled switch with affinity tag and method of use thereof | 加利福尼亚大学董事会 | 2024-04-16 | — | — | CN | disclosed |
| WO-2023220526-A1 | COMPOSITIONS AND METHODS FOR MODULATING DOPAMINE RECEPTOR ACTIVITY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-11-16 | — | — | WO | disclosed |
| CN-116669811-A | Compositions and methods for enhancing visual function | 加利福尼亚大学董事会 | 2023-08-29 | — | — | CN | disclosed |
| US-20230173090-A1 | COMPOSITIONS AND METHODS FOR MODULATING DOPAMINE RECEPTOR ACTIVITY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-06-08 | — | — | US | disclosed |
| WO-2023097186-A1 | COMPOSITIONS AND METHODS FOR ENHANCING VISUAL FUNCTION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-06-01 | — | — | WO | disclosed |
| EP-4172187-A1 | COMPOSITIONS AND METHODS FOR MODULATING DOPAMINE RECEPTOR ACTIVITY | The Regents of the University of California (US) | 2023-05-03 | — | — | EP | disclosed |
| EP-4158002-A1 | COMPOSITIONS AND METHODS FOR ENHANCING VISUAL FUNCTION | The Regents of the University of California (US) | 2023-04-05 | — | — | EP | disclosed |
| WO-2022006071-A1 | COMPOSITIONS AND METHODS FOR MODULATING DOPAMINE RECEPTOR ACTIVITY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-01-06 | — | — | WO | disclosed |
| WO-2021243086-A1 | COMPOSITIONS AND METHODS FOR ENHANCING VISUAL FUNCTION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-12-02 | — | — | WO | disclosed |
| US-20210369744-A1 | COMPOSITIONS AND METHODS FOR ENHANCING VISUAL FUNCTION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2021-12-02 | — | — | US | disclosed |
| US-8309350-B2 | Photoreactive regulator of protein function and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-11-13 | — | — | US | disclosed |
| US-20120190094-A1 | Photoreactive Regulator of Protein Function and Methods of Use Thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2012-07-26 | — | — | US | disclosed |
| US-8178496-B2 | Photoreactive regulator of glutamate receptor function and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-05-15 | — | — | US | disclosed |
| US-8114843-B2 | Photoreactive regulator of protein function and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-02-14 | — | — | US | disclosed |
| US-20110207213-A1 | Photoreactive Synthetic Regulator of Protein Function and Methods of Use Thereof | ENERGY, UNITED STATES DEPARTMENT OF | 2011-08-25 | — | — | US | disclosed |
| US-20100330607-A1 | PHOTOSWITCH-ENABLED ION CHANNEL ASSAY SYSTEM | PHOTOSWITCH BIOSCIENCES, INC. (US) | 2010-12-30 | — | — | US | disclosed |
| WO-2010151609-A1 | PHOTOSWITCH-ENABLED ION CHANNEL ASSAY SYSTEM | PHOTOSWITCH BIOSCIENCES INC. (US) | 2010-12-29 | — | — | WO | disclosed |
| WO-2010051343-A1 | PHOTOREACTIVE SYNTHETIC REGULATOR OF PROTEIN FUNCTION AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-05-06 | — | — | WO | disclosed |
| US-20090181454-A1 | PHOTOREACTIVE REGULATOR OF GLUTAMATE RECEPTOR FUNCTION AND METHODS OF USE THEREOF | ENERGY, UNITED STATE DEPARTMENT OF | 2009-07-16 | — | — | US | disclosed |
| US-20070128662-A1 | Photoreactive regulator of protein function and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2007-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210369744-A1 | COMPOSITIONS AND METHODS FOR ENHANCING VISUAL FUNCTION | PDE6C, UACA, EPHA2 | GSK3B 4410/4885CYP2A6 4645/4885CYP2B6 4649/4885 |
| US-20090181454-A1 | PHOTOREACTIVE REGULATOR OF GLUTAMATE RECEPTOR FUNCTION AND METHODS OF USE THEREOF | GRM2, GRM1, GRM3 | GSK3B 4744/4885CYP2A6 4490/4885CYP2B6 4669/4885 |
| US-20230173090-A1 | COMPOSITIONS AND METHODS FOR MODULATING DOPAMINE RECEPTOR ACTIVITY | PARK7, PRLHR, SNCA | GSK3B 2655/4885CYP2A6 4712/4885CYP2B6 4794/4885 |
| US-20070128662-A1 | Photoreactive regulator of protein function and methods of use thereof | PPP1R10, PPP6R3, ANKRD52 | GSK3B 4713/4885CYP2A6 4534/4885CYP2B6 4828/4885 |
| US-20110207213-A1 | Photoreactive Synthetic Regulator of Protein Function and Methods of Use Thereof | PPP1R10, PPP6R1, PPP6R3 | GSK3B 4782/4885CYP2A6 4626/4885CYP2B6 4823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.