Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 9/20 | 0.50 |
| ▸ | KDR | P35968 | 2/20 | 0.50 |
| ▸ | MST1R | Q04912 | 1/20 | 0.50 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6002914 | 0.92 | PDGFRB (0.49) | METKDRMST1RFGFR2SRC | |
| SCHEMBL6004897 | 0.89 | MET (0.48) | METKDRMST1RFGFR2 | |
| SCHEMBL6004278 | 0.82 | KDR (0.49) | METKDRSRCTGFBR1AXL | |
| SCHEMBL6004708 | 0.82 | TGFBR1 (0.52) | METKDRMST1RSRCTGFBR1 | |
| SCHEMBL6004255 | 0.81 | PDGFRB (0.51) | METKDRMST1RFGFR2SRC | |
| SCHEMBL6004082 | 0.81 | CBFB (0.37) | METKDRMST1RSRCTGFBR1 | |
| SCHEMBL6005275 | 0.80 | PDGFRB (0.52) | METKDRMST1RSRCTGFBR1 | |
| SCHEMBL3906631 | 0.78 | TGFBR1 (0.53) | FGFR2SRCTGFBR1 | |
| SCHEMBL6004880 | 0.78 | TGFBR1 (0.52) | METKDRMST1RSRCTGFBR1 | |
| SCHEMBL6004277 | 0.77 | NPSR1 (0.43) | METKDRSRCTGFBR1AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1724268-A1 | COMPOUND HAVING TGF-BETA INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | KIRIN BEER KABUSHIKI KAISHA (JP) | 2006-11-22 | — | — | EP | disclosed |