Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 8/20 | 0.48 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | MST1R | Q04912 | 1/20 | 0.48 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6005275 | 0.91 | PDGFRB (0.52) | METKDRMST1RPDGFRBPDGFRA | |
| SCHEMBL6005260 | 0.89 | MET (0.50) | METKDRMST1RFGFR2 | |
| SCHEMBL6005209 | 0.84 | MET (0.41) | METKDRMST1RFGFR2 | |
| SCHEMBL6004741 | 0.81 | SRC (0.46) | METKDRMST1RFGFR2PDGFRB | |
| SCHEMBL6002914 | 0.80 | PDGFRB (0.49) | METKDRMST1RFGFR2PDGFRB | |
| SCHEMBL6005293 | 0.80 | THRB (0.36) | — | |
| SCHEMBL6004233 | 0.80 | SRC (0.34) | PDGFRBPDGFRA | |
| SCHEMBL6004228 | 0.78 | AXL (0.34) | METKDRMST1RPDGFRBPDGFRA | |
| SCHEMBL6005256 | 0.77 | PDGFRB (0.36) | METKDRFGFR2PDGFRBPDGFRA | |
| SCHEMBL6004373 | 0.77 | PDGFRB (0.55) | FGFR2PDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1724268-A1 | COMPOUND HAVING TGF-BETA INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | KIRIN BEER KABUSHIKI KAISHA (JP) | 2006-11-22 | — | — | EP | disclosed |