Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.42 |
| ▸ | PGR | P06401 | 3/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GUSB | P08236 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6008256 | 0.82 | PGR (0.51) | SHBGALDH1A1NR3C1PGRADRA1A | |
| SCHEMBL10623707 | 0.80 | CYP19A1 (0.51) | — | |
| SCHEMBL7887183 | 0.72 | AR (0.58) | SHBGALDH1A1NR3C1PGRADRA1A | |
| SCHEMBL10601034 | 0.70 | PGR (0.50) | SHBGALDH1A1NR3C1PGRLMNA | |
| SCHEMBL6512260 | 0.70 | ALDH1A1 (0.46) | SHBGALDH1A1NR3C1PGRADRA1A | |
| SCHEMBL7882963 | 0.70 | LMNA (0.62) | SHBGALDH1A1NR3C1PGRLMNA | |
| SCHEMBL9472235 | 0.70 | LMNA (0.62) | SHBGALDH1A1NR3C1PGRLMNA | |
| SCHEMBL11788940 | 0.69 | LMNA (0.69) | SHBGALDH1A1NR3C1PGRADRA1A | |
| SCHEMBL10603383 | 0.69 | LMNA (0.69) | SHBGALDH1A1NR3C1PGRADRA1A | |
| SCHEMBL6008117 | 0.67 | NR3C1 (0.76) | SHBGALDH1A1NR3C1PGRADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003068314-A1 | PULMONARY ADMINISTRATION OF 6-ALPHA-ALKYLATED TESTOSTERONE DERIVATIVES FOR ANDROGEN REPLACEMENT THERAPY | PANTARHEI BIOSCIENCE B.V. (NL) | 2003-08-21 | — | — | WO | disclosed |