Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | TSHR | P16473 | 6/20 | 0.48 |
| ▸ | CASP1 | P29466 | 3/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6011414 | 0.94 | CASP1 (0.50) | ALDH1A1TSHRCASP1CNR1CNR2 | |
| SCHEMBL6011547 | 0.85 | CASP1 (0.42) | ALDH1A1TSHRCASP1CNR1CNR2 | |
| SCHEMBL3786356 | 0.84 | ALDH1A1 (0.48) | ALDH1A1TSHRCASP1CNR1CNR2 | |
| SCHEMBL6011208 | 0.83 | ALDH1A1 (0.46) | ALDH1A1TSHRCASP1CNR1CNR2 | |
| SCHEMBL6011409 | 0.80 | ALDH1A1 (0.42) | ALDH1A1CASP1CNR1CNR2NPC1 | |
| SCHEMBL3783969 | 0.80 | ALDH1A1 (0.50) | ALDH1A1TSHRCASP1CNR1CNR2 | |
| Formaldehyde SCHEMBL20572681 | 0.79 | ALDH1A1 (0.43) | ALDH1A1TSHRCASP1CNR1CNR2 | |
| SCHEMBL20572551 | 0.79 | ALDH1A1 (0.43) | ALDH1A1TSHRCASP1CNR1CNR2 | |
| SCHEMBL6011415 | 0.79 | ACHE (0.50) | ALDH1A1TSHRCASP1NPC1RAB9A | |
| SCHEMBL6011513 | 0.78 | RAB9A (0.47) | ALDH1A1CASP1CNR1CNR2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1355619-B1 | COLOURING AGENTS FOR KERATIN FIBRES CONTAINING (1.1'-BIPHENYL)-2.4-DIAMINE DERIVATIVES IN ADDITION TO NOVEL (1.1'-BIPHENYL)-2.4-DIAMINE-DERIVATIVES | WELLA AG (DE) | 2006-12-06 | — | — | EP | claimed |
| EP-1355619-B1 | COLOURING AGENTS FOR KERATIN FIBRES CONTAINING (1.1'-BIPHENYL)-2.4-DIAMINE DERIVATIVES IN ADDITION TO NOVEL (1.1'-BIPHENYL)-2.4-DIAMINE-DERIVATIVES | WELLA AG (DE) | 2006-12-06 | — | — | EP | disclosed |
| US-7056347-B2 | Coloring agents for keratin fibers containing (1,1′-biphenyl)-2,4-diamine derivatives in addition to novel (1,1′-biphenyl)-2,4-diamine-derivatives | WELLA AG (DE) | 2006-06-06 | — | — | US | disclosed |
| EP-1355619-A1 | COLOURING AGENTS FOR KERATIN FIBRES CONTAINING (1.1'-BIPHENYL)-2.4-DIAMINE DERIVATIVES IN ADDITION TO NOVEL (1.1'-BIPHENYL)-2.4-DIAMINE-DERIVATIVES | Wella Aktiengesellschaft (DE) | 2003-10-29 | — | — | EP | disclosed |
| US-20030172470-A1 | Colouring agents for keratin fibres containing (1.1'-biphenyl)-2.4-diamine derivatives in addition to novel (1.1'-biphenyl)-2.4-diamine-derivatives | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2003-09-18 | — | — | US | disclosed |
| WO-2002062307-A1 | COLOURING AGENTS FOR KERATIN FIBRES CONTAINING (1.1'-BIPHENYL)-2.4-DIAMINE DERIVATIVES IN ADDITION TO NOVEL (1.1'-BIPHENYL)-2.4-DIAMINE-DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 2002-08-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030172470-A1 | Colouring agents for keratin fibres containing (1.1'-biphenyl)-2.4-diamine derivatives in addition to novel (1.1'-biphenyl)-2.4-diamine-derivatives | KRT18, DSP, DSG1 | ALDH1A1 120/4885TSHR 4772/4885CASP1 967/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.