Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.49 |
| ▸ | ALPG | P10696 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.44 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6013 | 0.94 | ALOX15 (0.68) | ALOX15KMT2AMEN1ALPLALPI | |
| Fluoride SCHEMBL27943650 | 0.92 | ALOX15 (0.65) | ALOX15KMT2AMEN1ALPLALPI | |
| Hydrochloric Acid SCHEMBL8698847 | 0.90 | PPARG (0.50) | ALOX15KMT2AMEN1NPC1RAB9A | |
| Pyridine SCHEMBL2046976 | 0.83 | LMNA (0.55) | ALOX15KMT2AMEN1ALPLALPI | |
| SCHEMBL2117441 | 0.83 | ALOX15 (0.50) | ALOX15KMT2AMEN1HPGDSMN1; SMN2 | |
| Phenetole SCHEMBL28204387 | 0.82 | LTA4H (0.57) | ALOX15KMT2AMEN1NPC1RAB9A | |
| SCHEMBL2324869 | 0.82 | MAPT (0.58) | ALOX15KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4125546 | 0.82 | ALOX15 (0.63) | ALOX15KMT2AMEN1ALPLALPI | |
| SCHEMBL4643662 | 0.80 | ALOX15 (0.61) | ALOX15KMT2AMEN1ALPLALPI | |
| SCHEMBL3054083 | 0.79 | PLA2G4B (0.64) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998008839-A1 | COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED THIOPHENE LIBRARIES | ELI LILLY AND COMPANY (US) | 1998-03-05 | — | — | WO | disclosed |