Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 16/20 | 0.67 |
| ▸ | MMP2 | P08253 | 16/20 | 0.67 |
| ▸ | MMP9 | P14780 | 16/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | PELI1 | Q96FA3 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4670106 | 0.92 | TRPM2 (0.64) | MMP1MMP2MMP9MAPTPELI1 | |
| SCHEMBL6013326 | 0.92 | TRPM2 (0.64) | MMP1MMP2MMP9MAPTPELI1 | |
| SCHEMBL9973838 | 0.90 | MMP1 (0.65) | MMP1MMP2MMP9MAPTPELI1 | |
| SCHEMBL2779279 | 0.89 | MMP1 (0.75) | MMP1MMP2MMP9MAPT | |
| SCHEMBL2779276 | 0.89 | MMP1 (0.75) | MMP1MMP2MMP9MAPT | |
| SCHEMBL5351229 | 0.87 | TRPM2 (0.62) | MMP1MMP2MMP9MAPTPELI1 | |
| SCHEMBL4670083 | 0.87 | TRPM2 (0.62) | MMP1MMP2MMP9MAPTPELI1 | |
| SCHEMBL29913807 | 0.87 | TRPM2 (0.62) | MMP1MMP2MMP9MAPTPELI1 | |
| SCHEMBL4199523 | 0.85 | MMP1 (0.64) | MMP1MMP2MMP9MAPTMAOB | |
| SCHEMBL4199528 | 0.85 | MMP1 (0.64) | MMP1MMP2MMP9MAPTMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230131993-A1 | COMPOSITION COMPRISING AN AVENANTHRAMIDE OR AN ANALOGUE THEREOF WITH IMPROVED STABILITY | SYMRISE AG (DE) | 2023-04-27 | — | — | US | disclosed |
| US-20230131993-A1 | COMPOSITION COMPRISING AN AVENANTHRAMIDE OR AN ANALOGUE THEREOF WITH IMPROVED STABILITY | SYMRISE AG (DE) | 2023-04-27 | — | — | US | disclosed |
| US-20230129036-A1 | AVENANTHRAMIDE COMPOSITIONS WITH IMPROVED SOLUBILITY COMPRISING 4-HYDROXYPHENONE | SYMRISE AG (DE) | 2023-04-27 | — | — | US | disclosed |
| US-20230129036-A1 | AVENANTHRAMIDE COMPOSITIONS WITH IMPROVED SOLUBILITY COMPRISING 4-HYDROXYPHENONE | SYMRISE AG (DE) | 2023-04-27 | — | — | US | disclosed |
| US-20230118467-A1 | COSMETIC OR PHARMACEUTICAL USE OF AVENANTHRAMIDE L | SYMRISE AG (DE) | 2023-04-20 | — | — | US | disclosed |
| EP-1959915-B1 | MIXTURES COMPRISING ANTHRANILIC ACID AMIDES AND ANTIDANDRUFF AGENTS AS COSMETIC AND PHARMACEUTICAL COMPOSITIONS FOR ALLEVIATING ITCHING | SYMRISE AG (DE) | 2015-05-13 | — | — | EP | disclosed |
| US-8911795-B2 | Compositions comprising dihydroavenanthramide D and climbazole as cosmetic and pharmaceutical compositions for alleviating itching | SYMRISE AG (DE) | 2014-12-16 | — | — | US | disclosed |
| US-8911795-B2 | Compositions comprising dihydroavenanthramide D and climbazole as cosmetic and pharmaceutical compositions for alleviating itching | SYMRISE AG (DE) | 2014-12-16 | — | — | US | disclosed |
| US-8409552-B2 | Anthranillic acid amides and derivatives thereof as cosmetic and pharmaceutical active compounds | SYMRISE AG (DE) | 2013-04-02 | — | — | US | disclosed |
| US-8409552-B2 | Anthranillic acid amides and derivatives thereof as cosmetic and pharmaceutical active compounds | SYMRISE AG (DE) | 2013-04-02 | — | — | US | disclosed |
| US-8203016-B2 | Anthranilic acid amides and derivatives thereof as cosmetic and pharmaceutical agents | SYMRISE AG (DE) | 2012-06-19 | — | — | US | disclosed |
| US-8203016-B2 | Anthranilic acid amides and derivatives thereof as cosmetic and pharmaceutical agents | SYMRISE AG (DE) | 2012-06-19 | — | — | US | disclosed |
| US-20090297468-A1 | Mixtures Comprising Anthranilic Acid Amides and Cooling Agents as Cosmetic and Pharmaceutical Compositions for Alleviating Itching | SYMRISE GMBH & CO. KG (DE) | 2009-12-03 | — | — | US | disclosed |
| US-20090297468-A1 | Mixtures Comprising Anthranilic Acid Amides and Cooling Agents as Cosmetic and Pharmaceutical Compositions for Alleviating Itching | SYMRISE GMBH & CO. KG (DE) | 2009-12-03 | — | — | US | disclosed |
| US-20090226537-A1 | MIXTURES COMPRISING ANTHRANILIC ACID AMIDES AND ANTIDANDRUFF AGENTS AS COSMETIC AND PHARMACEUTICAL COMPOSITIONS FOR ALLEVIATING ITCHING | SYMRISE GMBH & CO. KG (DE) | 2009-09-10 | — | — | US | disclosed |
| US-20090226537-A1 | MIXTURES COMPRISING ANTHRANILIC ACID AMIDES AND ANTIDANDRUFF AGENTS AS COSMETIC AND PHARMACEUTICAL COMPOSITIONS FOR ALLEVIATING ITCHING | SYMRISE GMBH & CO. KG (DE) | 2009-09-10 | — | — | US | disclosed |
| EP-1886662-A1 | Anti-microbial compounds for treating bad breath | Symrise GmbH & Co. KG (DE) | 2008-02-13 | — | — | EP | disclosed |
| US-20080008660-A1 | Antimicrobially active compounds for treating bad breath | SYMRISE GMBH & CO. KG (DE) | 2008-01-10 | — | — | US | disclosed |
| US-20080008660-A1 | Antimicrobially active compounds for treating bad breath | SYMRISE GMBH & CO. KG (DE) | 2008-01-10 | — | — | US | disclosed |
| WO-2007062957-A1 | MIXTURES COMPRISING ANTHRANILIC ACID AMIDES AND ANTIDANDRUFF AGENTS AS COSMETIC AND PHARMACEUTICAL COMPOSITIONS FOR ALLEVIATING ITCHING | SYMRISE GMBH & CO. KG (DE) | 2007-06-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090297468-A1 | Mixtures Comprising Anthranilic Acid Amides and Cooling Agents as Cosmetic and Pharmaceutical Compositions for Alleviating Itching | H1-0, ASIC1, MCOLN1 | MMP1 1875/4885MMP2 3534/4885MMP9 3289/4885 |
| US-20230129036-A1 | AVENANTHRAMIDE COMPOSITIONS WITH IMPROVED SOLUBILITY COMPRISING 4-HYDROXYPHENONE | HPD, CYP4A22, PAH | MMP1 1164/4885MMP2 696/4885MMP9 1840/4885 |
| US-20090226537-A1 | MIXTURES COMPRISING ANTHRANILIC ACID AMIDES AND ANTIDANDRUFF AGENTS AS COSMETIC AND PHARMACEUTICAL COMPOSITIONS FOR ALLEVIATING ITCHING | H1-0, ASIC1, NHERF1 | MMP1 1102/4885MMP2 2746/4885MMP9 3318/4885 |
| US-20230131993-A1 | COMPOSITION COMPRISING AN AVENANTHRAMIDE OR AN ANALOGUE THEREOF WITH IMPROVED STABILITY | OAT, PIGS, HLA-A | MMP1 3885/4885MMP2 3658/4885MMP9 2745/4885 |
| US-20080008660-A1 | Antimicrobially active compounds for treating bad breath | CAT, LPO, GPX1 | MMP1 1177/4885MMP2 1501/4885MMP9 1691/4885 |
| US-20230118467-A1 | COSMETIC OR PHARMACEUTICAL USE OF AVENANTHRAMIDE L | TACR1, NPSR1, TACR2 | MMP1 1370/4885MMP2 2460/4885MMP9 1753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.