Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 12/20 | 0.67 |
| ▸ | RAB9A | P51151 | 12/20 | 0.67 |
| ▸ | MEN1 | O00255 | 5/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | AR | P10275 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.66 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.66 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.66 |
| ▸ | RELA | Q04206 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 6/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | TP53 | P04637 | 2/20 | 0.65 |
| ▸ | PKM | P14618 | 2/20 | 0.65 |
| ▸ | GMNN | O75496 | 1/20 | 0.65 |
| ▸ | THPO | P40225 | 1/20 | 0.65 |
| ▸ | BLM | P54132 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23555376 | 0.98 | NPC1 (0.65) | NPC1RAB9AMEN1KMT2AAR | |
| SCHEMBL12112870 | 0.89 | RAB9A (0.80) | NPC1RAB9AMEN1KMT2AAR | |
| SCHEMBL12249737 | 0.87 | NPC1 (0.53) | NPC1RAB9AMEN1KMT2AAR | |
| SCHEMBL12386970 | 0.86 | NPC1 (0.55) | NPC1RAB9AMEN1KMT2AAR | |
| SCHEMBL14505859 | 0.85 | NPC1 (0.58) | NPC1RAB9AMEN1KMT2AAR | |
| Trifluoroacetic Acid SCHEMBL4479324 | 0.84 | AR (0.54) | NPC1RAB9AMEN1KMT2AAR | |
| SCHEMBL706884 | 0.83 | RAB9A (0.71) | NPC1RAB9AMEN1KMT2AAR | |
| SCHEMBL31571831 | 0.83 | RAB9A (0.71) | NPC1RAB9AMEN1KMT2AAR | |
| 2-Phenylquinoline SCHEMBL29399739 | 0.83 | RAB9A (0.73) | NPC1RAB9AMEN1KMT2AAR | |
| 2-Phenylquinoline SCHEMBL44999 | 0.83 | RAB9A (0.73) | NPC1RAB9AMEN1KMT2AAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116466-B | Catalytic synthesis method of polysubstituted quinoline derivative | 浙江万里学院 | 2023-02-10 | — | — | CN | claimed |
| CN-111471009-A | Preparation method and application of 2-arylquinoline derivative | 安阳师范学院 | 2020-07-31 | — | — | CN | claimed |
| US-10125226-B2 | Scale-up process of bifunctionalized triblock copolymers with secondary and tertiary amines, with application in dewatering and desalting of heavy crude oils | INSTITUTO MEXICANO DEL PETROLEO (MX) | 2018-11-13 | — | — | US | claimed |
| CN-105801478-B | A kind of method that 2- aryl quinolines are prepared by cyclo other compounds | 常州大学 | 2018-05-25 | — | — | CN | claimed |
| CN-107459535-A | Polysubstituted quinoline coordinated iridium hybrid compound and preparation method and application thereof | 南京工业大学 | 2017-12-12 | — | — | CN | claimed |
| US-20140364566-A1 | SCALE-UP PROCESS OF BIFUNCTIONALIZED TRIBLOCK COPOLYMERS WITH SECONDARY AND TERTIARY AMINES, WITH APPLICATION IN DEWATERING AND DESALTING OF HEAVY CRUDE OILS | INSTITUTO MEXICANO DEL PETROLEO (MX) | 2014-12-11 | — | — | US | claimed |
| CN-119930511-A | Method for synthesizing N-heterocyclic compound by manganese complex catalysis under mild condition | 浙江工业大学 | 2025-05-06 | — | — | CN | disclosed |
| CN-115710223-B | Preparation method of 3-aryl quinolinone derivative | 广东工业大学 | 2024-05-10 | — | — | CN | disclosed |
| CN-117003695-A | Preparation method of 2, 3-disubstituted quinoline derivative | 广东工业大学 | 2023-11-07 | — | — | CN | disclosed |
| US-20230337527-A1 | ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME | LAPTO CO., LTD. (KR) | 2023-10-19 | — | — | US | disclosed |
| US-11770974-B2 | P active materials for organic photoelectric conversion layers in organic photodiodes | SONY CORPORATION (JP) | 2023-09-26 | — | — | US | disclosed |
| US-11770974-B2 | P active materials for organic photoelectric conversion layers in organic photodiodes | SONY CORPORATION (JP) | 2023-09-26 | — | — | US | disclosed |
| CN-111440181-B | Dipyrazolo seven-membered oxygen heterocyclic compound containing quinoline structure and synthetic method thereof | 烟台大学 | 2023-03-21 | — | — | CN | disclosed |
| WO-2008139287-A1 | AZETIDINE DERIVATIVES AND THEIR USE AS PROSTAGLANDIN E2 ANTAGONISTS | PFIZER LIMITED (GB) | 2008-11-20 | — | — | WO | disclosed |
| US-20080280877-A1 | Azetidines | PFIZER INC | 2008-11-13 | — | — | US | disclosed |
| US-20070252519-A1 | Novel thiophene-containing compound and thiophene-containing compound polymer, organic electroluminescent device, production method thereof, and image display medium | FUJI XEROX CO., LTD. (JP) | 2007-11-01 | — | — | US | disclosed |
| US-20070252519-A1 | Novel thiophene-containing compound and thiophene-containing compound polymer, organic electroluminescent device, production method thereof, and image display medium | FUJI XEROX CO., LTD. (JP) | 2007-11-01 | — | — | US | disclosed |
| WO-2007064773-A2 | ISOTOPICALLY-LABELED BENZOTHIAZOLE COMPOUNDS AS IMAGING AGENTS FOR AMYLOIDOGENIC PROTEINS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2007-06-07 | — | — | WO | disclosed |
| US-7115884-B1 | Self-encoding fiber optic sensor | TRUSTEES OF TUFTS COLLEGE (US) | 2006-10-03 | — | — | US | disclosed |
| EP-0124208-B1 | QUINOLINE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-04-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230337527-A1 | ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME | AOC1, ODC1, PIEZO1 | NPC1 1199/4885RAB9A 3157/4885MEN1 1661/4885 |
| US-11770974-B2 | P active materials for organic photoelectric conversion layers in organic photodiodes | JUP, L1CAM, EPCAM | NPC1 3239/4885RAB9A 2248/4885MEN1 3399/4885 |
| US-20080280877-A1 | Azetidines | PTGER2, PTGER1, PTGDR2 | NPC1 3819/4885RAB9A 883/4885MEN1 929/4885 |
| US-20070252519-A1 | Novel thiophene-containing compound and thiophene-containing compound polymer, organic electroluminescent device, production method thereof, and image display medium | ARL1, NOD1, NLRP1 | NPC1 1769/4885RAB9A 2145/4885MEN1 3286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.