Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 2/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6016037 | 0.82 | HDAC6 (0.39) | KDM4EPOLBCHRM2LMNA | |
| SCHEMBL6015701 | 0.79 | SMN1; SMN2 (0.42) | KDM4EPOLBLMNA | |
| SCHEMBL6016005 | 0.78 | L3MBTL1 (0.44) | KDM4EPOLBCHRM2 | |
| SCHEMBL6015885 | 0.75 | ALDH1A1 (0.43) | KDM4ESIGMAR1TSHR | |
| SCHEMBL6015708 | 0.73 | KDM4E (0.55) | KDM4EPOLB | |
| SCHEMBL6015768 | 0.71 | KDM4E (0.47) | KDM4E | |
| SCHEMBL16264664 | 0.71 | TERT (0.50) | TERTCCNA2CDK2KDM4EPOLB | |
| SCHEMBL6015755 | 0.71 | TERT (0.46) | TERTCCNA2CDK2KDM4E | |
| SCHEMBL27208122 | 0.70 | TDP1 (0.50) | TERTCCNA2CDK2TMEM97SIGMAR1 | |
| SCHEMBL18768839 | 0.70 | SIGMAR1 (0.60) | TERTCCNA2CDK2TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | claimed |
| EP-1181282-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-27 | — | — | EP | claimed |
| WO-2000075139-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-14 | — | — | WO | claimed |
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | disclosed |