Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 13/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | NCF1 | P14598 | 1/20 | 0.55 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015818 | 0.95 | LMNA (0.46) | CHKACA2NCF1PRMT6KDM4E | |
| SCHEMBL6015766 | 0.77 | ALDH1A1 (0.43) | CHKAKDM4EALDH1A1PARP1 | |
| SCHEMBL6015967 | 0.75 | L3MBTL3 (0.50) | ALDH1A1PARP1 | |
| SCHEMBL110133 | 0.71 | CHKA (1.00) | CHKACA2NCF1PRMT6KDM4E | |
| SCHEMBL16121577 | 0.71 | CHKA (1.00) | CHKACA2NCF1PRMT6KDM4E | |
| SCHEMBL19339191 | 0.71 | CHKA (0.64) | CHKACA2NCF1PRMT6KDM4E | |
| SCHEMBL13246320 | 0.70 | CHKA (0.77) | CHKACA2NCF1PRMT6KDM4E | |
| SCHEMBL12203051 | 0.70 | CHKA (0.77) | CHKACA2NCF1PRMT6KDM4E | |
| SCHEMBL18546870 | 0.70 | CHKA (0.77) | CHKACA2NCF1PRMT6KDM4E | |
| SCHEMBL2056181 | 0.70 | CHKA (0.77) | CHKACA2NCF1PRMT6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | claimed |
| EP-1181282-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-27 | — | — | EP | claimed |
| WO-2000075139-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-14 | — | — | WO | claimed |
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | disclosed |