Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015672 | 0.78 | EPHX1 (0.33) | EPHX1 | |
| SCHEMBL6016005 | 0.78 | L3MBTL1 (0.44) | — | |
| SCHEMBL6015701 | 0.78 | SMN1; SMN2 (0.42) | — | |
| SCHEMBL6016037 | 0.76 | HDAC6 (0.39) | — | |
| SCHEMBL6015645 | 0.73 | TERT (0.44) | — | |
| SCHEMBL18259979 | 0.71 | CHRM2 (0.51) | S1PR2S1PR4S1PR1S1PR3 | |
| SCHEMBL3193069 | 0.70 | MEN1 (0.53) | — | |
| SCHEMBL6015670 | 0.68 | EPHX1 (0.32) | EPHX1 | |
| SCHEMBL17423817 | 0.64 | — | — | |
| SCHEMBL6346133 | 0.64 | MAOA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | claimed |
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | disclosed |