Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015884 | 0.81 | HPGD (0.39) | ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL6015656 | 0.81 | ALDH1A1 (0.39) | ALDH1A1MAPTKMT2A | |
| SCHEMBL6015845 | 0.80 | KDM4E (0.31) | ALDH1A1HPGD | |
| SCHEMBL6016013 | 0.79 | ALDH1A1 (0.37) | ALDH1A1HPGDKMT2A | |
| SCHEMBL6015894 | 0.79 | ALDH1A1 (0.42) | ALDH1A1HPGDKMT2A | |
| SCHEMBL6015968 | 0.78 | ALOX15 (0.33) | EPHX1 | |
| SCHEMBL6015670 | 0.78 | EPHX1 (0.32) | EPHX1 | |
| SCHEMBL6016047 | 0.74 | HTR3A (0.39) | ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL6015948 | 0.73 | HTR3A (0.41) | ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL6015762 | 0.73 | HTR3A (0.41) | ALDH1A1MAPTHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | claimed |
| EP-1181282-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-27 | — | — | EP | claimed |
| WO-2000075139-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-14 | — | — | WO | claimed |
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | disclosed |