Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MERTK | Q12866 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3935756 | 0.79 | SMN1; SMN2 (0.47) | GPR119SMN1; SMN2KEAP1NFE2L2 | |
| SCHEMBL22750876 | 0.73 | ROCK2 (0.51) | NAAASMN1; SMN2ALDH1A1MAPK1HPGD | |
| Hydrochloric Acid SCHEMBL3936839 | 0.72 | NAAA (0.49) | NAAASMN1; SMN2ALDH1A1MAPK1HPGD | |
| SCHEMBL14393583 | 0.68 | RECQL (0.51) | SMN1; SMN2ALDH1A1MAPK1HPGDL3MBTL3 | |
| SCHEMBL13716059 | 0.68 | L3MBTL3 (0.51) | SMN1; SMN2ALDH1A1MAPK1HPGDL3MBTL3 | |
| SCHEMBL13128806 | 0.67 | GPR119 (0.56) | GPR119ABL1RIN1 | |
| SCHEMBL3960220 | 0.66 | MEN1 (0.66) | GPR119SMN1; SMN2ALDH1A1ABL1RIN1 | |
| SCHEMBL13716161 | 0.65 | L3MBTL3 (0.62) | SMN1; SMN2ALDH1A1L3MBTL3KDM4EPOLB | |
| SCHEMBL388120 | 0.65 | GPR119 (0.69) | GPR119USP30 | |
| SCHEMBL22503846 | 0.65 | MAPT (0.56) | SMN1; SMN2ALDH1A1MAPK1L3MBTL3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720874-A1 | 4-SUBSTITUTED PIPERIDINE DERIVATIVES | Bioaxone Therapeutique Inc. (CA) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005080394-A1 | 4-SUBSTITUTED PIPERIDINE DERIVATIVES | BIOAXONE THERAPEUTIQUE INC. (CA) | 2005-09-01 | — | — | WO | disclosed |