Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.46 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 9/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 7/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL692694 | 0.79 | ALOX15 (0.54) | ALOX15ALDH1A1SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL8466395 | 0.77 | CYP3A4 (0.45) | ALDH1A1CYP1A2HSP90AA1HSP90AB1GAA | |
| SCHEMBL11462442 | 0.77 | ALOX15 (0.41) | ALOX15ALDH1A1SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL78348 | 0.75 | CACNA1A (0.41) | ALOX15ALDH1A1SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL28163600 | 0.75 | ALDH1A1 (0.48) | ALOX15ALDH1A1SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL10939458 | 0.73 | ALOX15 (0.65) | ALOX15ALDH1A1SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL1277895 | 0.69 | ALOX15 (0.48) | ALOX15ALDH1A1SMN1; SMN2KDM4ECYP1A2 | |
| Bicarbonate SCHEMBL11614213 | 0.68 | ALDH1A1 (0.79) | ALOX15ALDH1A1SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL7185804 | 0.68 | CACNA1A (0.37) | ALOX15ALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL38604 | 0.67 | ALOX15 (1.00) | ALOX15ALDH1A1SMN1; SMN2KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060173107-A1 | Graftable hindered amine light stabilizers | CIBA SPECIALTY CHEMICALS CORP. | 2006-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060173107-A1 | Graftable hindered amine light stabilizers | IDO1, MAOA, TPH1 | ALOX15 300/4885ALDH1A1 50/4885SMN1; SMN2 1615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.