SCHEMBL60196

SCHEMBL60196

CC(C)(C)OC(=O)NC1CCCCC1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.68
EPHX1 P07099 9/20 0.66
BTK Q06187 1/20 0.65
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
CTSK P43235 2/20 0.51
HDAC4 P56524 1/20 0.51
HDAC1 Q13547 1/20 0.51
HDAC6 Q9UBN7 1/20 0.51
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
MAPT P10636 1/20 0.50
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50
CYP3A4 P08684 1/20 0.50
EPHX2 P34913 1/20 0.50
PDK1 Q15118 1/20 0.49
PDK2 Q15119 1/20 0.49
PDK3 Q15120 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28804033 1.00 GAA (0.68) GAAEPHX1BTKCA1CA2
Ethane SCHEMBL27689700 0.98 GAA (0.66) GAAEPHX1BTKCA1CA2
SCHEMBL1829584 0.98 BTK (0.67) GAAEPHX1BTKCA1CA2
Bicarbonate SCHEMBL1457456 0.96 BTK (0.66) GAAEPHX1BTKCA1CA2
Bicarbonate SCHEMBL1580534 0.94 BTK (0.68) GAAEPHX1BTKCA1CA2
SCHEMBL369297 0.94 BTK (0.72) GAAEPHX1BTKCA1CA2
SCHEMBL999662 0.93 GAA (0.60) GAAEPHX1BTKCA1CA2
Methyl Alcohol SCHEMBL9686628 0.92 BTK (0.70) GAAEPHX1BTKCA1CA2
Acetic Acid Methyl Ester SCHEMBL7025319 0.91 BTK (0.59) GAAEPHX1BTKCA1CA2
Bicarbonate SCHEMBL486564 0.90 BTK (0.73) GAAEPHX1BTKCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 508 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117800875-A Preparation method of trans- (N-Boc-4-aminocyclohexyl) acetic acid 泰州精英化成医药科技有限公司 2024-04-02 CN claimed
CN-1682702-A Method for preparing pharmaceutical composition capable of inhibiting postinfectious viral protease ALBERT LAB (US) 2005-10-19 CN claimed
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PEPTIDREAM INC (JP) 2026-01-15 US disclosed
US-20250353841-A1 HETEROCYCLIC COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE HUFF SARAH ELIZABETH (US) 2025-11-20 US disclosed
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2024-12-05 US disclosed
CN-119013277-A TYK2 degrading agent and application thereof 凯麦拉医疗公司 2024-11-22 CN disclosed
CN-113302184-B 1,3, 4-Oxadiazolinone compounds and medicaments 日本新药株式会社 2024-11-22 CN disclosed
CN-118696041-A Macrocyclic BTK inhibitors 克罗斯费尔肿瘤学控股有限公司 2024-09-24 CN disclosed
CN-118574613-A Methods of treating cancer 凯麦拉医疗公司 2024-08-30 CN disclosed
US-20240239749-A1 MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS AND METHODS ESCIENT PHARMACEUTICALS INC (US) 2024-07-18 US disclosed
US-20240239749-A1 MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS AND METHODS ESCIENT PHARMACEUTICALS INC (US) 2024-07-18 US disclosed
US-5856307-A Peptide derivatives as kininogenase inhibitors ASTRA AKTIEBOLAG (SE) 1999-01-05 US disclosed
US-5847135-A Inhibitors of interleukin-1β converting enzyme VERTEX PHARMACEUTICALS, INCORPORATED (US) 1998-12-08 US disclosed
US-5783563-A Method for treatment or prophylaxis of venous thrombosis ASTRA AKTIEBOLAG 1998-07-21 US disclosed
US-5780631-A ANTICOAGLUANT ASTRA AKTIEBOLAG (SE) 1998-07-14 US disclosed
US-5723444-A ENZYME INHIBITORS AND ANTICOAGULANTS ASTRA AB (SE) 1998-03-03 US disclosed
US-5716929-A THERAPY FOR INFLAMMATION, AUTOIMMUNE DISEASES VERTEX PHARMACEUTICALS, INC. (US) 1998-02-10 US disclosed
EP-0672653-B1 Process for producing isocyanates MITSUBISHI GAS CHEMICAL CO (JP) 1998-01-14 EP disclosed
CN-1025676-C Non-peptidic renin inhibitors PFIZER (US) 1994-08-17 CN disclosed
CN-1034366-A The blood vessel tension peptide protoenzyme inhibitor of non-peptide PFIZER (US) 1989-08-02 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250353841-A1 HETEROCYCLIC COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE HTT, HYPK, ATXN2 GAA 36/4885EPHX1 4056/4885BTK 2743/4885
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF NSUN3, BCAT1, SLC43A1 GAA 2026/4885EPHX1 4238/4885BTK 2244/4885
US-20240239749-A1 MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS AND METHODS MRGPRX2, MRGPRX1, MRGPRX4 GAA 2874/4885EPHX1 1506/4885BTK 2827/4885
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES BCAT1, BCAT2, PELP1 GAA 3046/4885EPHX1 4857/4885BTK 4780/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.