Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 1/20 | 0.51 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30871059 | 1.00 | ATM (0.51) | ATMTDP1CTSKHCAR3TSHR | |
| SCHEMBL2554714 | 0.87 | AKR1C2 (0.54) | HCAR3MAPTLMNAHTTALDH1A1 | |
| SCHEMBL4427078 | 0.85 | HDAC6 (0.56) | ATMTDP1CTSKCASP6HDAC1 | |
| SCHEMBL22734863 | 0.85 | CASP6 (0.62) | TDP1HCAR3TSHRMAPTCASP6 | |
| SCHEMBL6415835 | 0.84 | MAPT (0.55) | ATMTDP1CTSKTSHRMAPT | |
| SCHEMBL24185865 | 0.83 | HTT (0.56) | ATMTDP1CTSKHCAR3HTT | |
| SCHEMBL30663390 | 0.83 | CTSK (0.48) | ATMTDP1CTSKTSHRMAPT | |
| SCHEMBL1418448 | 0.83 | CTSK (0.54) | ATMTDP1CTSKHCAR3MAPT | |
| SCHEMBL385099 | 0.82 | TSHR (0.68) | TSHRMAPTLMNAHTTPOLB | |
| SCHEMBL17486764 | 0.82 | GPR35 (0.51) | HCAR3TSHRMAPTCASP6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4605392-A1 | METHODS FOR TREATING CANCER | Antares Therapeutics, Inc. (US) | 2025-08-27 | — | — | EP | disclosed |
| US-20250084055-A1 | DIHYDROQUINOLINONES FOR MEDICAL TREATMENT | C4 THERAPEUTICS, INC. (US) | 2025-03-13 | — | — | US | disclosed |
| US-12091397-B2 | Dihydroquinolinones for medical treatment | C4 THERAPEUTICS, INC. | 2024-09-17 | — | — | US | disclosed |
| WO-2024086809-A1 | METHODS FOR TREATING CANCER | SCORPION THERAPEUTICS, INC. (US) | 2024-04-25 | — | — | WO | disclosed |
| CN-111278816-B | Dihydro quinolinones | C4医药公司 | 2024-03-15 | — | — | CN | disclosed |
| US-20230192643-A1 | DIHYDROQUINOLINONES FOR MEDICAL TREATMENT | C4 THERAPEUTICS, INC. (US) | 2023-06-22 | — | — | US | disclosed |
| CN-113004252-B | Aryl imidazole derivative and application thereof | 江苏先声药业有限公司 | 2023-06-09 | — | — | CN | disclosed |
| CN-113004252-A | Aryl imidazole derivative and application thereof | 江苏先声药业有限公司 | 2021-06-22 | — | — | CN | disclosed |
| US-7402696-B2 | Benzene compounds | AJINOMOTO CO., INC. (JP) | 2008-07-22 | — | — | US | disclosed |
| US-20070105899-A1 | Benzene compounds | AJINOMOTO CO., INC. (JP) | 2007-05-10 | — | — | US | disclosed |
| US-7138420-B2 | Substituted benzimidazole compounds | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2006-11-21 | — | — | US | disclosed |
| US-20050203158-A1 | Substituted benzimidazole compounds | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2005-09-15 | — | — | US | disclosed |
| EP-1529046-A1 | SUBSTITUTED BENZIMIDAZOLE COMPOUNDS | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2005-05-11 | — | — | EP | disclosed |
| WO-2004014905-A1 | SUBSTITUTED BENZIMIDAZOLE COMPOUNDS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2004-02-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12091397-B2 | Dihydroquinolinones for medical treatment | CRBN, RBX1, ADRM1 | ATM 849/4885TDP1 2908/4885CTSK 2922/4885 |
| US-20230192643-A1 | DIHYDROQUINOLINONES FOR MEDICAL TREATMENT | CRBN, RBX1, ADRM1 | ATM 849/4885TDP1 2908/4885CTSK 2922/4885 |
| US-20250084055-A1 | DIHYDROQUINOLINONES FOR MEDICAL TREATMENT | CRBN, RBX1, ADRM1 | ATM 849/4885TDP1 2908/4885CTSK 2922/4885 |
| US-20070105899-A1 | Benzene compounds | ACACB, ACACA, FABP4 | ATM 293/4885TDP1 3735/4885CTSK 3476/4885 |
| US-20050203158-A1 | Substituted benzimidazole compounds | ITK, BLK, SBK1 | ATM 331/4885TDP1 2104/4885CTSK 26/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.