Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 3/20 | 0.42 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RBP4 | P02753 | 2/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17672966 | 0.70 | TAS2R14 (0.54) | TAS2R14FABP4ALDH1A1MEN1KMT2A | |
| SCHEMBL6025625 | 0.70 | TAS2R14 (0.43) | TAS2R14FABP4ALDH1A1MEN1KMT2A | |
| SCHEMBL11178354 | 0.68 | TAS2R14 (0.55) | TAS2R14FABP4ALDH1A1MEN1KMT2A | |
| SCHEMBL12303989 | 0.64 | TAS2R14 (0.50) | TAS2R14FABP4ALDH1A1MEN1KMT2A | |
| SCHEMBL221518 | 0.64 | LMNA (0.62) | TAS2R14FABP4ALDH1A1MEN1KMT2A | |
| SCHEMBL30449216 | 0.64 | LMNA (0.62) | TAS2R14FABP4ALDH1A1MEN1KMT2A | |
| Alcohol SCHEMBL28201640 | 0.64 | LMNA (0.53) | TAS2R14FABP4ALDH1A1MEN1KMT2A | |
| SCHEMBL12471016 | 0.64 | ALDH1A1 (0.46) | L3MBTL1ALDH1A1HDAC6GAALMNA | |
| SCHEMBL15925029 | 0.64 | RXFP1 (0.57) | TAS2R14FABP4ALDH1A1MEN1KMT2A | |
| SCHEMBL8558161 | 0.64 | TAS2R14 (0.60) | TAS2R14FABP4ATMALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685119-A1 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | Abbott Laboratories (US) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005049594-A1 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | ABBOTT LABORATORIES (US) | 2005-06-02 | — | — | WO | disclosed |