Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3145891 | 0.86 | THRA (0.57) | THRATHRBLMNATSHRALDH1A1 | |
| SCHEMBL3507489 | 0.86 | THRA (0.57) | THRATHRBLMNATSHRALDH1A1 | |
| SCHEMBL3507493 | 0.86 | THRA (0.57) | THRATHRBLMNATSHRALDH1A1 | |
| SCHEMBL9323967 | 0.83 | ALDH1A1 (0.59) | LMNATSHRALDH1A1GAASMN1; SMN2 | |
| SCHEMBL10686479 | 0.83 | LMNA (0.54) | LMNAALDH1A1NPC1BCHETYR | |
| SCHEMBL2519102 | 0.83 | THRA (0.52) | THRATHRBLMNATSHRALDH1A1 | |
| SCHEMBL16335562 | 0.81 | BCHE (0.43) | THRATHRBLMNAALDH1A1BCHE | |
| SCHEMBL2516365 | 0.81 | MAPT (0.52) | LMNAALDH1A1BCHETYRACHE | |
| SCHEMBL131893 | 0.80 | LMNA (0.49) | LMNAALDH1A1NPC1BCHETYR | |
| SCHEMBL6550407 | 0.80 | MEN1 (0.48) | LMNABCHETYRACHEGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020027737-A1 | A SOLID-SUPPORTED HYDROXY AMINO ACID AND A SOLID-SUPPORTED AMINO ALCOHOL | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2020-02-06 | — | — | WO | disclosed |
| US-20140343227-A1 | Diketopiperazine Forming Dipeptidyl Linker | LONZA AG (CH) | 2014-11-20 | — | — | US | disclosed |
| US-20140343227-A1 | Diketopiperazine Forming Dipeptidyl Linker | LONZA AG (CH) | 2014-11-20 | — | — | US | disclosed |
| US-8802819-B2 | Diketopiperazine forming dipeptidyl linker | LONZA LTD. (CH) | 2014-08-12 | — | — | US | disclosed |
| US-8802819-B2 | Diketopiperazine forming dipeptidyl linker | LONZA LTD. (CH) | 2014-08-12 | — | — | US | disclosed |
| WO-2012055509-A1 | DIKETOPIPERAZINE FORMING DIPEPTIDYL LINKER | LONZA LTD (CH) | 2012-05-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140343227-A1 | Diketopiperazine Forming Dipeptidyl Linker | FAP, IAPP, DNPEP | THRA 4309/4885THRB 4377/4885LMNA 2112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.